Growing Teeth Formula

Researchers at the  Institute of Biotechnology of the University of Helsinki developed a computer model reproducing population-level variation in  teeth. This has implications for growing correctly shaped teeth.

With more than 15 years of work, Jukka Jernvall and his team have compiled data on the evolutionary development of mammal teeth and the main aspects of a formula for making teeth emerging.

According to a mathematical computer model, a rather simple basic formula seems to be behind the complex gene puzzle resulting in tooth formations. The jungle of gene networks has a ‘patterning kernel’ which regulates the variation of teeth among individuals. It is possible that human teeth from the incisors to the molar teeth may result from a single factor which regulates cell division.

The researchers have investigated their model on seal teeth. The Ladoga ringed seal collection  at the University of Helsinki served as an ideal population sample  because dentitions are highly variable.

Isaac Salazar-Ciudad and Jukka Jernvall. A computational model of teeth and the developmental origins of morphological variation. Nature, 2010.

5 Responses to Growing Teeth Formula

  1. Toothhater April 14, 2010 at 2:28 am #

    I wonder if the simple basic formula is related to fractals? Romanesco broccoli anyone?
    .-= Toothhater´s last blog ..Toothless Twins =-.

  2. Implant Dentist Chandler April 21, 2010 at 11:18 am #

    I’d really like to this simple formula and how it could affect dental practice.
    .-= Implant Dentist Chandler´s last undefined ..Response cached until Thu 22 @ 19:12 GMT (Refreshes in 23.91 Hours) =-.

  3. Gilbert Dentists May 12, 2010 at 9:18 pm #

    Where can I get a copy of the study?

  4. wisdom May 15, 2010 at 7:58 pm #

    If you are interested in this study it is available in Nature at

    however you must either subscribe to Nature or pay a fee to view the study.

    (I have access through my university)

  5. How to become a dental hygienist February 11, 2011 at 12:46 am #

    This study is veeeery interesting. I guess I will buy it shortly.

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