Antibodies Present Mean Healthier Teeth and Gums
Antibodies present in people with good oral health could become the first tool for dental professionals to assess a patient’s probable response to periodontal disease treatments. The antibody is to a protein called HtpG, the bug that makes it is Porphyromonas gingivalis, an important pathogen in periodontal disease. The antibody also has potential as a vaccine candidate, according to Charles Shelburne, assistant research scientist at the U-M School of Dentistry. Researchers discovered that the HtpG antibodies were present in much lower amounts in people with periodontal disease, and in much higher concentrations in those with healthier teeth and gums. Typically, antibodies are elevated in people with disease, because they help fight the disease. “What has been seen in periodontal disease over the last 30-40 years is that patients with periodontal disease have higher levels of antibodies to the bacteria associated … Read more