Creating 3-D Mini Brains

Researchers at the Houston Methodist Research Institute are making 3-D mini brains from human stem cells. They hope that such models can help with research on repairing the nervous system after injury or disease of the brain. The researchers have developed a way to reduce the time required to grow these brain models which will allow for faster testing of drugs and study of disease-causing mutations. For the first time when the researchers put the cells together, they dramatically changed their morphological complexity, size, and shape. They believe they look like cells you would see in the human brain. Cells traditionally grown in lab cultures are put on a flat petri dish where they are often manipulated and thus their interactions are disturbed. The form, structure, and developmental growth of the brain’s cells are thus not able to be reproduced … Read more