Tag Archives | amoxicillin

How Effective is Antimicrobial Prophylaxis in Oral Procedures

An interesting article titled “Effectiveness of Antimicrobial Prophylaxis in Preventing the Spread of Infection as a Result of Oral Procedures: A Systematic Review and Meta-Analysis” appears in the 2016 Journal of Oral and Maxilofacial Surgery written by J. A. Moreno-Drada and H. A. Garcia-Perdomo (vol. 74, pp. 1313-1321). The article seeks to explore the effectiveness of prophylactic antibiotics (such as amoxicillin) for preventing localized infections of the oral cavity, neck, and thoracic cavity in patients undergoing oral procedures. Bacteremia is well known to occur after dental procedures. Severe complications as a result of infections from bacteremia have been reported. Based on expert opinions, it has been recommended that prophylaxis be given to patients at high risk before manipulation of the gingiva or periapical region of the teeth and before perforation of the oral mucosa during dental procedures. However the use of prophylactic antibiotics is controversial. In some cases this could lead to antiobiotic resistance. In the face of bacterial resistance, infections can continue to disseminate through the anatomic planes and pathways with lower resistance, leading to complications, such as Ludwig angina, thoracic empyema, septicemia, necrotizing fasciitis, cavernous sinus thrombosis, mediastinal retinitis, cerebral abscess, meningitis, and bacterial endocarditis. The study explored articles with women and men older than 18 years who underwent oral procedures and received a prophylactic antibiotic (single preoperative dose) or another intervention for the prevention of […]

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Exploring Giving Antibiotics Before Third Molar Surgery (Wisdom Teeth Removal) in Spain

An issue that one asks when having third molar surgery (wisdom teeth removal) is one whether should have antibiotics administered before or after surgery (or not at all). See for example http://www.teethremoval.com/antibiotic_resistance.html In a recent article appearing in J Evid Base Dent Pract 2012, issue 12, pp. 149-150, Manal A. Awad, reviewed a study exploring amoxicillin administration to those who were having wisdom teeth extracted. The original study was titled “Efficacy of amoxicillin treatment in preventing postoperative complications in patients undergoing third molar surgery: a prospective, randomized, double-blind controlled study,” by Lopez-Cedrun JL, Pijoan JI, Fernandez S, and Santamaria J, Hernandez G and appeared in the electronic 2011 version pages 5 -14, issue 69, number 6. It is well known that amoxicillin is useful in treating oral infections. In the study 123 healthy patients between the ages of 18 and 46 years which included mostly females (90) were randomly divided into 3 groups: 1) received amoxicillin preoperatively (n = 39), 2) received placebo (n = 44), and 3) received amoxicillin postoperatively (n = 40).  The patients in the study were having at least 1 impacted wisdom teeth removed. Patients and clinicians were blinded as to what group they were in […]

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