Articaine versus Bupivacaine Anesthetic Effectiveness for Lower Teeth Extraction

An interesting article titled “A Comparative Evaluation of Anesthetic Effectiveness of 4% Articaine vs 0.5% Bupivacaine for Lower Molar Tooth Extraction” appears in Cureus in December 16, 2022, written by Tenglikar P, Manas A, Sahoo A, et al. (vol. 14, no. 12, pp. e32611). The article discusses the differences in the effectiveness of two common local anesthesia agents used in dentistry to control pain. The authors set out to explore the the effectiveness of 0.5% bupivacaine with 4% articaine in lower tooth extraction based on duration of anesthesia, onset, and pain perception along with observing blood pressure and heart rate. Today lidocaine (lignocaine) is extensively used as a local anesthestic agent in dentistry to control pain. Other anesthestic agents exists including bupivacaine and articaine. The authors conducted a randomized controlled study of patients having lower teeth extracted from June 2017 to October … Read more

Propofol-Remifentanil Versus Propofol-Ketamine for Third Molar Surgery

A study titled “Comparison of Propofol-Remifentanil Versus Propofol-Ketamine Deep Sedation for Third Molar Surgery” appears in the 2012 Anesthesia Progress journal. The authors of the study set out to better determine what anesthetic to provide during third molar (aka wisdom teeth) surgery. In the study, two drug combinations for use as deep sedation during oral surgery were evaluated. Patients in a control group received a continuous intravenous infusion of propofol-remifentanil,  and patients in an experimental group received a continuous intravenous infusion of propofol-ketamine. This study was double blind in that neither patients nor surgeons were aware of which treatment was given. In this study, 37 patients  were monitored while sedated for respiratory, heart rate, and blood pressure stability. Emergence from the effects of anesthesia and total recovery time were recorded. In addition, patients and surgeons were both asked to rate … Read more