Tag Archives | antibiotics

The Effect of a Single Dose of Antibiotics Prior to Wisdom Teeth Surgery

An interesting article titled “A Systematic Review on Effect of Single-Dose Preoperative Antibiotics at Surgical Osteotomy Extraction of Lower Third Molars” appears in the 2016 Journal of Oral and Maxilofacial Surgery and written by Karoline Brørup Marcussen and et. al. (vol. 74, pp. 693-703). The authors sought to conduct a systematic review of randomized controlled trials to evaluate the effectiveness of a single dose of preoperative antibiotics for preventing infection and alveolar osteitis [dry socket] in lower wisdom tooth surgery performed with osteotomy. Using antibiotic prophylaxis to reduce the incidence and severity of postoperative complications in surgical removal of impacted lower wisdom teeth is controversial. All randomized controlled trials  (RCTs) evaluating the effect of all types of prophylactic antibiotics administered 20 to 120 minutes preoperatively versus no antibiotics or placebo on the incidence of infection after surgical removal of lower impacted wisdom up to 1 week after surgery, were reviewed by the authors. In the search, 196 search hits were found. From these, 50 potentially relevant reports and 9 relevant reviews were identified. From these 7 RCTs were included and 3 additional were turned up in other searchers. Three RCTs reported infections, 4 RCTs reported alveolar osteitis, and 3 RCTs reported both infections and alveolar osteitis as outcomes. Finally a total of  1,390 patients from 10 RCTs were included. The meta-analysis showed that the use of antibiotics significantly reduced […]

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Exploring Antibiotic Use with Lower Wisdom Teeth Surgery

An interesting article titled “Correlation of antibiotic prophylaxis and difficulty of extraction with post operative inflammatory complications in the lower third molar surgery” appears in the 2014 British Journal of Oral and Maxillofacial Surgery and written by J. Y. Lee and et al. (vol. 52, pp. 54-57). The article set out to investigate the correlation between antibiotic prophylaxis, difficulty of extraction, and postoperative complications of lower wisdom teeth. The authors say that indiscriminate antibiotic prophylaxis can lead to antimicrobial resistance and a shift in the microbial population. The authors performed a retrospective analysis of extraction of lower wisdom teeth performed at Korea University Guro Hospital over a two year time frame starting in January 2010. The authors only included cases in which cefditoren pivoxil was prescribed as an antibiotic. In addition, patients that were kept in a hospital due to postoperative complications were excluded from the study. The patients were divided into two groups those given antibiotics and those not given antibiotics. A total of 1222 extractions in 890 patients were included in the study. The authors found that overall the difficulty of extraction and post operative complications were significantly associated (p=0.03). In cases grouped by similar class of difficulty, it was found that there was no significant correlation […]

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Patient’s Perception of Antibiotic Need After Teeth Removal

An interesting article titled “Patients’ Perception of the Need for Antibiotics Following Routine Tooth Extraction,” appears in the May 2015 issue of the Journal of Oral and Maxilofacial Sugery and written by Charles D. Boxx and Daniel M. Laskin (vol. 73, issue 5). The article seeks to perform a study of 120 patients having teeth removed in Richmond, Virginia, at Virginia Commonwealth University (VCU), to see their perception of antibiotic need. The patients were asked to complete a questionnaire about whether they expected to be prescribed antibiotics after tooth extraction, whether they would request them if not prescribed and the reason why, and whether they would expect to be prescribed antibiotics for a toothache or a dental abscess. The patients were further asked if they had ever requested antibiotics from a medical doctor for a cold. The patients also indicated their gender, age, and level of education. The study group consisted of 61 women and 59 women with an average age of 48 years. Eighty of the 120 patients expected (66.7%) to receive an antibiotic after tooth removal. There was found to be no statistical difference in the age and education of the positive and negative groups. Seventy percent of […]

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Heart Infections on the Rise in Dental Patients After Antibiotic Reductions

In March 2008, the National Institute for Health and Care Excellence issued guidelines recommending that dentists should no longer give antibiotics before invasive treatments to people who are considered at risk of developing a life threatening heart infection. The life threatening heart infection is known as infective endocarditis and 40% of all cases are caused by bacteria in the mouth. Researchers at the University of Sheffield set out to explore the impact of these guidelines. It was found that an increase in cases of infective endocarditis was observed above what was expected. In March 2013, this increase accounted for an extra 35 cases of infective endocarditis per month. The researchers found that the number of  prescribed antibiotic prophylaxis fell by 89% from 10,900 prescriptions per month, before the 2008 NICE guidelines, to 1,235 a month by March 2008. The researchers understand that infective endocarditis is a rare infection and want the guideline committees to re-evaluate the benefits and risks of giving antibiotic prophylaxis. It is important to understand that maintaining high standards of oral hygiene can lead to reducing the number of bacteria in the mouth and reducing the number of invasive dental procedures that need to be performed. The […]

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