bone

Could a Medication One Day Be Given Instead of Braces to Control Tooth Movement?

by

Recent research from Tokyo Medical and Dental University (TMDU) showed that osteocytes have a crucial role in orthodontic tooth movement as the major source of receptor activator of nuclear factor kappa-Β ligand (RANKL) which is a protein critical to bone remodeling. It is  known that the differentiation of osteoclasts is regulated by RANKL. However, the source of RANKL in the periodontal tissue during orthodontic tooth movement was not previously identified. Now thanks to the research team it is know that osteocytes mainly express RANKL and play a key role in the remodeling of  bone surrounding teeth during orthodontic tooth movement. To explore this issue, the researchers used an orthodontic tooth movement model in which open coil springs were inserted between teeth of mice to move first molars. They then injected a neutralizing antibody against RANKL intended to reduce tooth movement. The … Read more

Does Fluoride Cause Additional Hip Fractures?

by

Researchers are interested in studying fluoride and it’s possible benefits and risks due to it commonly being in water supplies of communities. This is because fluoride is known to help prevent cavities. Even so, some question if putting fluoride in everyone’s water is the right thing to do as some people could experience problems from the water. For example, several studies have shown Large Amounts of Fluoride Consumed by Young Children Leads to Fluorosis. Hence, it is beneficial to minimize fluoride exposure to young children. Others have looked at the opposite end of the age spectrum: old people. Researchers in Sweden have investigated the possibility that fluoride in the water can lead to additional hip fractures. The study consisted of a large amount of Swedish residents who were exposured to fluoride levels with the researchers testing a hypothesis that there … Read more