ibuprofen

Nonsteroidal anti-inflammatory drugs better than opioids for pain after dental extractions

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An interesting article titled “Acute Postoperative Pain Due to Dental Extraction in the Adult Population: A Systematic Review and Network Meta-analysis,” written by A. Miroshnychenko and et. al appears in the 2023 edition of the Journal of Dental Research. The article seeks to conduct a systematic review and meta-analysis to assess tto compare the effectiveness of 10 different pharmacological treatments including acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids, to the management of acute pain after dental tooth extractions. Further the article looked at the pain associated with pulpitis or its complications. The authors were motived to conduct the review based on the opioid crisis occuring in North America which has been discussed before on this site, see for example the posts Assessing the Impact of Three Day Opioids Limits for Dentists, Dentists Overprescribing Opioids to Adults in the U.S., and Reducing … Read more

Combining ibuprofen and acetaminophen for wisdom teeth surgery pain management

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Before on this site the hazards of opioids prescribed for surgeries like wisdom teeth extraction has been discussed. Instead of taking an opioid like Vicodin which contains hydrocodone or another opioid that contains oxycodone an alternative patients may have if their oral surgeon is willing is to take a combination of ibuprofen and acetaminophen. This combination has been discussed in many articles on the past on this site such as Reducing Opioids in Oral and Maxillofacial Surgery, New Research Being Conducted at Rutgers for Opioid Alternatives Could Lead to Less Potential Drug Abuse for those Having Wisdom Teeth Surgery, and Oral and Maxillofacial Surgeons Current Perspectives on Opioid Prescribing. Patients may have questions about the right dosage level, there side effects, and if they work as well as opioids. According to a white paper by the American Association of Oral … Read more

Does Intravenous Ibuprofen Reduce Pain After Wisdom Teeth Surgery?

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An interesting article titled “Does Single-Dose Preemptive Intravenous Ibuprofen Reduce Postoperative Pain After Third Molar Surgery? A Prospective, Randomized, Double-Blind Clinical Study” appears in the 2019 edition of the Journal of Oral and Maxillofacial Surgery. The article explores if intravenous ibuprofen given either shortly before or after wisdom teeth surgery has any any effect on pain experienced in the subsequent 24 hours. In the article a study is conducted using 75 patients who presented at Erciyes University in Turkey over the time period from March to October 2018 for removal of impacted lower wisdom teeth. The 75 patients were randomly divided into 3 groups with 25 patients in each. The first group of patients received 800 mg of intravenous ibuprofen 60 minutes before surgery and intravenous placebo 60 minutes after surgery, the second group of patients received intravenous placebo 60 … Read more

Comparing Ibuprofen and Etodolac on Swelling and Pain After Wisdom Teeth Removal

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An interesting article titled “Comparative Assessment of the Effect of Ibuprofen and Etodolac on Edema, Trismus, and Pain in Lower Third Molar Surgery: A Randomized Clinical Trial” appears in the 2016 Journal of Oral an Maxilofacial Surgery written by Julio Cesar Silva de Oliveira and et al. (vol. 74, pp. 1524-1530). The authors set out to explore if ibuprofen or etodolac is more effective in managing pain, swelling, and trismus after wisdom teeth removal. After wisdom teeth removal symptoms such as swelling, pain and limited mouth opening (trismus) can present. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed for the rapid relief of moderate pain in inflammatory conditions and soft tissue trauma. The mechanism of action of NSAIDs is the inhibition of the release of cyclooxygenase (COX), an enzyme that is responsible for the production of prostaglandins (PGs). Ibuprofen is an NSAID which inhibits COX-1 and COX-2. Etodolac differs from other NSAIDs by being … Read more