Tag Archives | migraine

Sphenopalatine Ganglion (SPG) Block for Headache Relief

Sphenopalatine Ganglion (SPG) block has been shown to help provide migraine headache relief for both children and adults. A small flexible catheter is inserted into each nostril and a local anesthetic is administered to the SPG, a nerve bundle thought to be associated with migraines, located at the back of the nose.  The anesthetic briefly disables the SPG and can disrupt and reset the headache circuit, which can break a cycle of severe migraines. A SPG block takes almost immediate effect with relief potentially lasting for many months. The SPG blocks have been performed in children. A child qualifies for the treatment if he/she has been diagnosed with a severe migraine and that migraine has not responded favorably to first-line medications and treatments. This form of treatment can be performed in an outpatient setting by an interventional radiologist. It can […]

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Exploring the Prevalence of Generalized Anxiety Disorder in Adults with Migraine

Researchers at the University of Toronto have shown that generalized anxiety disorder is more common among adults who have migraines than those without migraine (6% vs. 2%). The link between migraine and generalized anxiety disorders was partially explained by the high prevalence of debilitating chronic pain (30%) and problems in managing household responsibilities (28%) among those with migraine. The researchers were not surprised chronic pain played a role in the association between migraines and generalized anxiety disorders. The unpredictable and uncontrollable nature of migraine pain can be anxiety producing as it can interfere with family and work responsibilities without warning. The study found men with migraine had almost double the odds of generalized anxiety disorder compared with women with migraine. The researchers found this result to be surprising because in the general population, women are more likely than men to develop […]

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Migraine treament with monoclonal antibodies

Migraine headaches affect around 6 to 8% of males and 10 to 12% of females. It is one of the top five neurological conditions and costs people healthy lives. There is little research on how the current preventative treatments for migraine work. Researchers have speculated that the suppression of cortical spreading depression could be a process at play. Typically migraine patients are given beta-blockers such as propranolol and metroprolol, anticonvulsants valproate and topiramate, and the calcium channel bocker flunarizine as first line medications. These drugs have been shown in randomized placebo controlled studies to reduce the frequency of migraine attacks. A new treatment option could be placed in monoclonal antibodies that target a neuropeptide called CGRP (Calcitonin Gene-related Peptide). CGRP plays is thought to play a key role in headaches. CGRP receptor antagonists have been developed for the treatment of acute […]

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A new marker in blood for migraine?

An interesting article titled “Interictal, circulating sphingolipids in women with episodic migraine: A case-control study” written by B. L. Peterlin and et al. discusses that a new marker in blood may have been found for episodic migraine (Neurology, 2015). Episodic migraine is when a patient has less than 15 headaches per month. The researchers performed a study with 52 women with episodic migraine and 36 women who did not have any headaches. They all had to undergo a neurologic exam, gave blood samples, and had their body mass index measured. The women in the study with migraine had an average of 5.6 headache days per month. The blood samples were tested for a group of lipids that are known to help regulate inflammation in the brain and participate in energy homeostasis. The study found the total levels of lipids called ceramides were decreased in women […]

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Finding Relief From Headaches with Meditation

According to research published in the journal Headache, meditation may help migraine headache sufferers. Researchers have known that stress can be a trigger for headaches but there hasn’t been a whole lot of research done to evaluate meditation and it’s benefits. The researchers set out to develop a study to assess the feasibility, safety,and effects of a yoga and meditation intervention known as mindfulness-based stress reduction (MBSR) in adults who suffer from migraines. In the study 19 adults were randomly assigned to 2 groups with 10 of the adults receiving MBSR and 9 receiving standard medical care. The participants attended 8 weekly classes in order to learn MBSR techniques and were told to practice 45 minutes on their own 5 days per week. The participants in the study were evaluated before and after the trial period using measures such as mindfulness, […]

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