migraine

New Drugs to Help Prevent Migraine in Development

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Earlier this year at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, two studies were presented which may be intriguing for those who suffer from migraine headaches. The studies explored the use of potential drugs to prevent migraine attacks from occurring. In both studies monoclonal antibodies were explored which target the calcitonin gene related peptide CGRP. Researchers have believed that CGRP is useful for migraine but drugs were never developed for it previously. One of the studies looked at 163 people who suffered from migraine between 5 and 14 days per month. These individuals received either a placebo or a IV dose of a drug ALD403. The individuals were followed for a period of 24 weeks. Those who received ALD403 had an average of 5.6 fewer migraine days per month compared to 4.6 fewer migraine days per month for … Read more

New Blood Pressure Medication for Migraines

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A new study by the Norway and the Norwegian University of Science and Technology shows that a blood pressure medication, candesartan, is as effective as propranolol which is prescribed to prevent migraine. Further, candesartan may work better for those migraine suffers who don’t find propranolol to be useful. The study by the norwegian researchers was a triple blind test which means that neither patients nor doctors nor those who analyzed the results knew whether the patients had been given the drug or a placebo. Seventy two patients took part in the study and all patients were affected by migraine attacks at least twice a month. The patients used each treatment candesartan, propranolol, or placebo for 12 weeks and also underwent four weeks before start and finish between each treatment without anything. As such each patient was tested for nearly a … Read more

Can Making Less Money Lead to Migraines?

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A study appearing by researchers in Neurology explores whether migraines limit the educational and career achievements of individuals which can lead to a lower income status. The study also explores whether problems related to low income such as stressful life events and poor access to health care increase the likelihood of developing migraines. The researchers used data from the American Migraine Prevalence and Prevention Study, a US national sample containing responses of 162,705 men and  women aged 12 and older who had some migraine symptoms able to be identified, their age, and household income. The authors defined low income as less than $22,500 per year for the household and high income as $60,000 per year or more. The researchers found the remission rate when migraines stop occurring for a time or for good was the same regardless of income. The researchers … Read more

Chewing Gum Linked to Headaches

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An interesting study and findings regarding a link between headaches and gum chewing has come from Tel Aviv University. The article was published in Pediatric Neurology and looked at 30 patients between 6 and 19 with chronic headache and who were big gum chewers. The patients were told to stop chewing gum. After 1 month, nineteen of the patients had their headache go away and 7 additional patients in the group had a decrease in the severity and frequency of their headaches. Twenty six of the patients were then told to go back to chewing gum like they used to and they all said their previous symptoms returned within days. The researchers speculate that temporomandibular joint (TMJ) dysfunction may be the likely trigger at bay. The researchers believe that TMJ overuse is causing the headaches. Other possibilities were suggested such as … Read more

Blood Levels in Fat Cells May Help Predict Migraine

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A new study appearing in the journal Headache: The Journal of Head and Face Pain, looks at people experiencing two to twelve migraine headaches a month. In this study researchers found that measuring a fat-derived protein called adiponectin before and after migraine treatment is useful in revealing if headache patients felt pain relief or not. The researchers of the study are hopeful that finding this potential biomarker for migraine of adiponectin may be used for developing new and better migraine treatment options. Finding better treatment options for migraine sufferers is lucrative because roughly 36 million Americans suffer from migraine headaches which can last longer than 4 hours at a time. Women are three times to get migraines when compared to men. In the study the researchers collected blood from 20 women who visited 3 different headache clinics for an acute … Read more