Tag Archives | migraine

Sleep Deprivation and the Biological Mechanisms of Chronic Migraine Headache

Scientists from the Missouri State University’s Center for Biomedical & Life Sciences have found new research to suggest sleep deprivation leads to changes in the levels of key proteins that facilitate events involved in the underlying pathology of migraine. “Previous clinical data support a relationship between sleep quality and migraine,” said Paul L. Dunham, Ph.D. “so we used an established model of sleep deprivation to measure levels of proteins that lower the activation threshold of peripheral and central nerves involved in pain transmission during migraine. We found that REM sleep deprivation caused increased expression of the proteins p38, PKA, and P2X3, which are known to play an important role in initiating and sustaining chronic pain.” “So little is known about the biological mechanisms that underlie how certain factors trigger a migraine attack,” said David Dodick, M.D., “This is important work […]

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Headache Causes Difficulty Tuning out Visuals

A recent study from researchers from Scotland’s Glasgow Caledonian University has come out with implications for headache sufferers. The research suggests migraine sufferers even when they do not have a headache may process visual cues better in an environment with few visual distractions. The researchers asked migraine sufferers to pick out a small disk of light with visual noise was present which severed as a visual distraction. Without the visual noise, people prone to migraine could identify the light disk about as well as the control group. When the noise was added, migraine sufferers performed significantly worse. The study demonstrated migraine sufferers with auras were the actually the most affected by the addition of visual noise. This research has practical implications for those who suffer from headache and migraine. It may thus be best to avoid environments with a lot […]

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Gene Linked to Increased Heart Disease in Migraine Women

Heart disease is the leading cause of death and stroke is the third leading cause of death in the United States. Women who experience migraine with aura appear to be at an increased risk of heart disease and stroke if they have a certain gene. For the study, researchers followed 25,001 Caucasian women for the occurrence of cardiovascular disease, including heart attacks and ischemic stroke. About 18 percent of the women in the study had a history of migraine while 40 percent of those with active migraine reported migraine with aura. Migraine with aura can be described as neurological symptoms that usually last for about 30 minutes and most often lead to visual disturbances. The women were also tested for a certain gene variant in the methyleneterahydrofolate reductase gene. During a 12-year follow-up period, 625 cardiovascular disease events occurred. The […]

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