Propofol-Remifentanil Versus Propofol-Ketamine for Third Molar Surgery

A study titled “Comparison of Propofol-Remifentanil Versus Propofol-Ketamine Deep Sedation for Third Molar Surgery” appears in the 2012 Anesthesia Progress journal. The authors of the study set out to better determine what anesthetic to provide during third molar (aka wisdom teeth) surgery. In the study, two drug combinations for use as deep sedation during oral surgery were evaluated. Patients in a control group received a continuous intravenous infusion of propofol-remifentanil,  and patients in an experimental group received a continuous intravenous infusion of propofol-ketamine. This study was double blind in that neither patients nor surgeons were aware of which treatment was given. In this study, 37 patients  were monitored while sedated for respiratory, heart rate, and blood pressure stability. Emergence from the effects of anesthesia and total recovery time were recorded. In addition, patients and surgeons were both asked to rate … Read more