opioid

Intravenous Ketamine During Surgery

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A review articled carried out by the Cochrane Database of Systematic Reviews titled “Perioperative intravenous ketamine for acute postoperative pain in adults” written by Brinck et al. in 2018 (no. 12, art. no. CD012033) explored the efficacy and safety of intravenous ketamine in adults for pain management while having surgery under general anesthesia. The authors sought randomized, double-blind, controlled trials for inclusion in their analysis. The main outcomes were opioid consumption and pain intensity at 24 and 48 hours after surgery. The authors included 130 studies with 8,341 participants. Types of surgery included wisdom teeth extraction and among many others like lumbar fusion surgery, anterior cruciate ligament (ACL) repair, abdominal surgery, and elective caesarean section. The researchers found by looking at 65 of these studies that perioperative intravenous ketamine reduced postoperative opioid consumption over 24 hours by 8 mg morphine … Read more

Record Numbers Predicted to Die from Opioids in the US

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As has been covered on this site before, opioid abuse which can stem from wisdom teeth surgery at a young age is a major challenge in countries like the U.S. There are many stories of families where a young person in their teenage or twenty years has their wisdom teeth taken out and then are exposed to opioids to control pain. This exposure can lead to them become potentially addicted to opioids and then later die as a result of this addiction. Thus, finding alternatives to opioids for surgery like wisdom teeth removal is important to help curb a disturbing trend. See posts like Dentists Overprescribing Opioids to Adults in the U.S., New Research Being Conducted at Rutgers for Opioid Alternatives Could Lead to Less Potential Drug Abuse for those Having Wisdom Teeth Surgery, and Studies and Opinions on Opioids … Read more

FDA warns about dental problems from buprenorphine

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The U.S. Food and Drug Administration (FDA) has issued a safety concern regarding the medication buprenorphine which is a medication used to treat opioid use disorder, acute pain, and chronic pain. Buprenorphine is often used to reduce opioid withdrawal symptoms and the desire to use opioids, without causing the cycle of highs and lows associated with abusing opioid. The FDA warning issued on January 12, 2022, states that dental problems have occured when patients take medicines containing buprenorphine that are dissolved in the mouth. In the warning, the FDA said that the dental problems can include those of tooth decay, cavities, loss of teeth, and oral infections, and can occur in those without prior dental issues. As a result of this warning, the risk of dental problems occuring will be added to the prescribing information and the patient Medication Guide … Read more

Low-Dose Naltrexone as An Alternative to Opioids for Wisdom Teeth Removal

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Before on this site numerous posts have discussed how many feel dentists and oral surgeons prescribe (or in the past have prescribed) too many opioids for their patients to help manage pain of dental procedures like wisdom teeth removal, see for example the post Do Oral Surgeons Give Too Many Opioids for Wisdom Teeth Removal?. In recent years there have been investigations into alternatives to opioids for dental procedures and also for chronic pain management when opioids in the past were more regularly prescribed for as well. One such approach is to prescribe a combination of ibuprofen and acetaminophen as discussed in the articles New Research Being Conducted at Rutgers for Opioid Alternatives Could Lead to Less Potential Drug Abuse for those Having Wisdom Teeth Surgery and Reducing Opioids in Oral and Maxillofacial Surgery. Recently, there have been articles and … Read more

Reducing Opioids in Oral and Maxillofacial Surgery

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An interesting article titled “Opioid Prescribing Can Be Reduced in Oral and Maxillofacial Surgery Practice,” written by Tatch appears in the 2019 edition of the Journal of Oral and Maxillofacial Surgery. In the article the author discusses the results of implementing an office protocol for pain management to reduce opioid use in oral and maxillofacial surgery during a three year time period. Results from a similar study were presented previously in a post titled Oral and Maxillofacial Surgeons Current Perspectives on Opioid Prescribing. In the article the author discusses how a risk of opioids is dependence which can develop after just one week of using. The author came up with a 3-year retrospective study to measure changes in opioid use after the introduction of an office protocol which was designed to offer alternatives to pain relief. In the study a … Read more