Low sensitivity to pain due to gene mutation

A research team from UCL has identified a rare mutation that causes members of one family to have low sensitivity to pain. The researchers hope that the results could be used to identify new treatments for chronic pain. One in ten people experience moderate to severe disabling chronic pain. Understanding congenital analgesia, a rare inherited condition that reduces the capacity to feel physical pain, could lead to new pain relief therapies. Two mutations causing congenital analgesia are being explored by researchers working with pharmaceutical firms, but no breakthrough drugs have been developed. The researchers studied an Italian family, the Marsilis, which has six people with a distinctive pain response unique to them. The members of this family can burn themselves without feeling any pain. The family has normal intraepidermal nerve fibre density which means they are not missing any nerves. … Read more

Why is Pain in the Face and Head Worse than the Rest of the Body?

Researchers have found why pain from the head and face can be more disruptive, and emotionally draining than pain in other parts of the body. The researchers found that sensory neurons from the head and face are wired directly into the brain’s principal emotional signaling hubs, while sensory neurons from elsewhere in the body are connected only indirectly to this hub. People consistently rate pain of the head and face as more disruptive and emotionally draining than pain in other parts of the body. The results may help lead toward more effective treatments for pain mediated by the craniofacial nerve, including chronic headaches and neuropathic face pain. Usually doctors focus on treating the sensation of pain, but this work demonstrates that doctors need to also treat the emotional aspects of pain. Pain signals from the head and face compared to those … Read more

How to Avoid Opioid Addiction When You’re Prescribed Pain Medication

Have you been prescribed pain medication, but worry that you might become addicted to it? This fear is common, and it’s also valid. Some pain medications can alter your brain in a way that doesn’t just keep the pain away, but can leave your body craving more than you once needed to have the same effect. Long-term use of pain medication, especially, can cause an addiction. Here’s what you need to know to avoid becoming addicted to your pain medication. What Pain Medications are Addictive? From drugs to help prevent migraines to prescriptions for menstrual pain, there is a medication for just about any type of pain you can have, from mild to severe. Some pose a rare chance of an addiction, whereas others can have more serious consequences. Unfortunately, virtually any medication carries a risk of causing an addiction … Read more

How to treat your wisdom teeth during pregnancy

It is completely safe to have regular dental cleanings while you are pregnant. Many women experience pregnancy-related gingivitis and other dental issues during pregnancy, and regular cleaning may help minimize the chances of developing a serious problem. However, we can’t always predict what will happen, and sometimes serious problems arise that need to be addressed. The topic of dental treatments during pregnancy is one that gets a lot of attention, and the information can be confusing. One issue that is particularly controversial is the issue of treating wisdom teeth. What can you do if you experience pain and swelling related to your wisdom teeth during pregnancy? Is it safe to treat them, or do you have to endure the pain until after you have your baby? The bottom line is that you should schedule an appointment with your dentist immediately … Read more

Using Povidone Iodine After Wisdom Teeth Removal

The article titled “Effect of Low-Concentration Povidone Iodine on Postoperative Complications After Third Molar Surgery: A Pilot Split-Mouth Study” written by Hamid Mahmoud Hashemi and et. al. appears in the January 2015 issue of the Journal of Oral and Maxillofacial Surgery (vol. 73, issue 1). The article discusses polyvinylpyrrolidone iodine which is a highly potent antiseptic solution known for its bactericidal activity. The authors performed a prospective randomized split mouth study of patients undergoing surgical removal of impacted mandibular wisdom teeth to evaluate whether diluted povidone iodine can be used as an irrigant and coolant and if it has any effect on common postoperative sequelae, including swelling, pain, and trismus. A total of 30 healthy patients (18 to 25 yr old) with bilateral impacted mandibular wisdom with similar position and degree of impaction were recruited at Tehran University in Iran … Read more