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Treating with Platelet Rich Fibrin After Wisdom Teeth Removal

An interesting article titled “Evaluation of Treatment Outcome After Impacted Mandibular Third Molar Surgery With the Use of Autologous Platelet-Rich Fibrin: A Randomized Controlled Clinical Study,” appears in the Journal of Oral and Maxilofacial Surgery written by Nilima Kumar and et al. (vol 73, pp. 1042-1049). The article sets out to explore the effect of platelet-rich fibrin (PRF) on postoperative pain, swelling, trismus, periodontal healing near the second molar, and progress of bone regeneration in upper wisdom teeth extraction sockets. Clinicians have identified a subpopulation of patients having wisdom teeth removed that are at ‘‘high risk’’ for periodontal defects after wisdom teeth removal (such as greater than 26 years old, pre-existing periodontal defects [attachment level, >3 mm; probing depth, >5 mm]; and horizontal or mesioangular impaction). The authors studied a patient sample that consisted of 31 patients with mesioangular or horizontal upper impacted wisdom teeth. Patients in the study were randomized by the closed-envelope method and divided into 2 groups. In one group, 16 patients had a impacted mandibular wisdom tooth surgically removed and PRF was placed into the extraction socket followed by flap approximation. The control group  had 15 patients treated with surgical removal of the impacted mandibular wisdom […]

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