Tag Archives | prophylaxis

How Effective is Antimicrobial Prophylaxis in Oral Procedures

An interesting article titled “Effectiveness of Antimicrobial Prophylaxis in Preventing the Spread of Infection as a Result of Oral Procedures: A Systematic Review and Meta-Analysis” appears in the 2016 Journal of Oral and Maxilofacial Surgery written by J. A. Moreno-Drada and H. A. Garcia-Perdomo (vol. 74, pp. 1313-1321). The article seeks to explore the effectiveness of prophylactic antibiotics (such as amoxicillin) for preventing localized infections of the oral cavity, neck, and thoracic cavity in patients undergoing oral procedures. Bacteremia is well known to occur after dental procedures. Severe complications as a result of infections from bacteremia have been reported. Based on expert opinions, it has been recommended that prophylaxis be given to patients at high risk before manipulation of the gingiva or periapical region of the teeth and before perforation of the oral mucosa during dental procedures. However the use of prophylactic antibiotics is controversial. In some cases this could lead to antiobiotic resistance. In the face of bacterial resistance, infections can continue to disseminate through the anatomic planes and pathways with lower resistance, leading to complications, such as Ludwig angina, thoracic empyema, septicemia, necrotizing fasciitis, cavernous sinus thrombosis, mediastinal retinitis, cerebral abscess, meningitis, and bacterial endocarditis. The study explored articles with women and men older than 18 years who underwent oral procedures and received a prophylactic antibiotic (single preoperative dose) or another intervention for the prevention of […]

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