Wisdom teeth could hold regenerative medicine answers

An interesting article titled “A single-cell atlas of human teeth” written by Pierfrancesco Pagella et al. appears in iScience (vol. 24, no. 102405, May 21, 2021). In the article the researchers analyzed five wisdom teeth that had been extracted to conduct a comprehensive single-cell atlas of the human tooth. The cells studied came from these five wisdom teeth and were extracted by dentists in Zurich. Isolating the cells from these wisdom teeth may have introduced variability between samples and some cells may not have survived the isolation process. Even so, the study found novel insights into how stem cells work which could help answer questions in regenerative medicine. In the study, the researchers at the University of Zurich and ETH Zurich used single-cell RNA sequencing to investigate cells present in dental pulp and the periodontium. The researchers compared patterns of … Read more

Storing Wisdom Teeth Stem Cells

In recent years there have been articles discussing harvesting stem cells located in wisdom teeth with the hope that one day they could be used to heal damaged cells in the body. Nowadays some oral surgeons will offer patients the option after extracting their wisdom teeth to bank dental stem cells. There are a few extra steps to preserve stem cells from wisdom during surgery. All one has to do is to put the teeth into a packaging kit and then send them off for processing using a shipping service like FedEx, UPS, or USPS. It makes it easy if the oral surgeon or oral surgeons office can assist with the packaging and shipping of wisdom teeth after surgery as someone who just had surgery probably won’t be up for it. However, if the location one has wisdom teeth does … Read more