Using Stem Cells from Teeth to Regrow Injured Teeth

An interesting article titled “Deciduous autologous tooth stem cells regenerate dental pulp after implantation into injured teeth,” by Xuan et al. appears in Science Translational Medicine (vol. 10, no. 455, 2018, Published August 22, 2018). The article discusses the results of a clinical trial using stem cells extracted from baby teeth to regrow tissue in teeth that have been injured. In the past articles on this site have discussed storing wisdom teeth stem cells with the hopes that they could one day be used to heal other body tissues. While this study did not use stem cells from wisdom teeth, but instead stem cells from baby teeth, it helps demonstrate some of the possibilities that may exist in the future. In the study by Xuan et al., the authors were motivated by some previous studies with mice. A further motivation … Read more

Researchers Find And Harvest Stem Cells In Wisdom Teeth

There’ve been great advancements in how stem cells could be used to treat disease in the future, such as how wisdom teeth stem cells could repair corneas in the eye. One of the latest news stories is how a team of dentists and engineers from the University Of Nevada in Las Vegas have found ways to harvest stem cells located in wisdom teeth, with the idea that these could later be used to heal damaged cells in the body. Why is this important? It offers benefits to the medical world while making wisdom teeth more useful than ever before. Many Extracted Teeth Are Still Healthy Many people have teeth pulled out. In fact, in the U.S., research has found that around 75-80 percent of people have wisdom teeth removed because they’re troublesome. However, the team of dentists and engineers from Las Vegas has found that many … Read more

Wisdom Teeth Stem Cells Could be Used For The Eye

A new interesting study has shown that wisdom teeth stem cells could be turned into cells of the eye’s cornea. The stem cells could one day be used to repair cornea scaring due to infection or injury. Thus wisdom teeth stem cells could play a role in helping to treat corneal blindness which affects millions of people in the world. It is typically treated with transplants of donor corneas. Of course, with any transplants, shortages can occur and rejection of donor tissue can occur. This can result in permanent vision loss. Using one patient’s own stem cells from their wisdom teeth would avoid these issues. The research was conducted in association with the University of Pittsburgh. Their Department of Opthalmology showed that stem cells of dental pulp obtained from a wisdom tooth extraction could be turned into corneal stromal cells … Read more

Stem Cells Can Help Fight Inflammatory Disease

A recent study shows that stem cells found in mouth tissue can help relieve inflammatory disease. The stem cells studied are gingival mesenchymal stem cells (GMSC) which are found in gum tissue in the mouth. Similarly to other types of stems cells, GMCS develop into cells that effect the immune system. The study found two differet types of GMSC: those that arise from the mesoderm layer of cells during embryonic development (M-GMSC) and those that come from cranial neural crest cells (N-GMSC).  The two types of stem cells vary substantially in their benefits. N-GMSC was found to be easier to change into other cells include neural and cartilage-producing cells. N-GMSC was found to have more of a healing effect on inflammatory disease. When the researchers transplanted N-GMSC into mice with dextrate sulfate sodium-induced colitis, which is an inflamed condition of … Read more

Monkey Stem Cells Stimulate Brain

Researchers at the Yerkes National Primate Research Center, Emory University, have discovered dental pulp stem cells can stimulate growth and generation of several types of neural cells. They suggest dental pulp stem cells show promise for use in cell therapy and regenerative medicine, particularly therapies associated with the central nervous system. Dental stem cells are adult stem cells, one of the two major divisions of stem cell research. Adult stem cells have the ability to regenerate many different types of cells, promising great therapeutic potential, especially for diseases such as Huntington’s and Parkinson’s. Already, dental pulp stem cells have been used for regeneration of dental and craniofacial cells. Yerkes researcher Anthony Chan, DVM, PhD, and his team of researchers placed dental pulp stem cells from the tooth of a rhesus macaque into the hippocampal areas of mice. The dental pulp … Read more