Long Term Consequences of Traumatic Brain Injury (TBI)

An interesting article appears in the journal PLOS ONE looking at the consequences of traumatic brain injury (TBI) using rate models. The researchers used rat models and found that overtime TBI results in progressive brain deterioration characterized by elevated inflammation and suppressed cell regeneration. Long-term neurological deficits from TBI related to inflammation may cause more severe secondary injuries and even predispose people to neurodegenerative diseases later in life. Traumatic brain injuries are important to study since troops in the U.S. military have increasingly suffered TBI from improvised explosive devices. One of the coauthors from the journal article (Dr. Paul R. Sanberg) says “Progressive injury to hippocampal, cortical and thalamic regions contributes to long-term cognitive damage post-TBI. Both military and civilian patients have shown functional and cognitive deficits resulting from TBI.” In the study researchers looked at different parts of the … Read more

Headaches after Traumatic Brain Injury Highest in Adolescents and Girls

A recent study has been conducted by the Seattle Children’s Research Institute and appeared in Pediatrics, vol 129, number 1, January 2012, pages 1 to 9, titled Headache After Pediatric Traumatic Brain Injury: A Cohort Study, wirtten by Heidi K. Blume and et al. The article discusses how in the adult population 18% to 33% of those who suffer from traumatic brain injury suffer from headaches 1 year after the injury. In the child population most of the investigations conducted have been small, retrospective, lacked a control, or involved only short term follow up. Chronic headaches with children are associated with interference in social function, parental productivity, and poor quality of life. The study randomly selected 1507 patients with TBI and 495 controls with arm injury (AI) for the study. However, some patients were not reachable, others were inegligible, and … Read more