Inflammation Plays a Role in Alzheimer’s disease

Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn have shown that inflammatory mechanisms from the brain’s immune system drive the progression of Alzheimer’s disease. The research provides new insights into the pathogenetic mechanisms that may hold the potential for preventing Alzheimer’s disease before symptoms show up. Alzheimer’s disease is a neurodegenerative condition that eventually leads to dementia. The disease is associated with the aggregation of small proteins called “Amyloid-beta” (Abeta), known as “plaques,” that accumulate in the brain and are believed to harm neurons. Prior studies have shown deposits of Abeta trigger inflammatory mechanisms by the brain’s immune system. Researchers believe that deposition and spreading of Abeta likely precede any clinical symptoms by decades. Even so researchers do not fully understand the processes responsible and thus believe by doing so that effective treatments to target Alzheimer’s … Read more

Is it okay for dentists to not tell a patient everything wrong?

An interesting article titled “Is it unethical to not present a patient’s treatment plan in its entirety?” is written by Emily Ishkanian and appears in the June 2016 issue of JADA. The article discusses that a dentist gets a new patient in for only an examination, cleaning, and radiographs. However after the exam, the dentist determined that the patient has extensive treatment needs. The dentist is concerned that if they tell the patient everything wrong then the patient will be scared to return to the office. The patient went to the dentist for just a standard visit. It is likely they thought there was nothing wrong with their oral health. The dentist is concerned that the patient will suspect overtreatment which could lead them to decline the treatment plan or seek another opinion. The ADA code says that dentists need to be truthful and … Read more

Reducing Migraines with Cosmetic Eyelid Surgery

An interesting article titled “Non-Endoscopic Deactivation of Nerve Triggers in Migraine Headache Patients,” appears in the 2014 issue of the journal Plastic and Reconstructive Surgery written by Lisa Gfrerer and et. al. The article describes a method to screen and select patients for a surgical migraine treatment technique used by plastic and reconstructive surgeons. The surgery decompresses nerves that trigger migraines. The surgery used is stated to be an alternative to an endoscopic approach used which works down from the scalp under the skin as the other approach is not always suitable. The surgery discussed involves incisions through the upper eyelid and the study demonstrated that this approach was equally as effective for the deactivation of nerves involved in migraine headaches. In the study migraine headaches were completely eliminated in roughly 51% of the patients while around 20% of the patients … Read more

New Blood Pressure Medication for Migraines

A new study by the Norway and the Norwegian University of Science and Technology shows that a blood pressure medication, candesartan, is as effective as propranolol which is prescribed to prevent migraine. Further, candesartan may work better for those migraine suffers who don’t find propranolol to be useful. The study by the norwegian researchers was a triple blind test which means that neither patients nor doctors nor those who analyzed the results knew whether the patients had been given the drug or a placebo. Seventy two patients took part in the study and all patients were affected by migraine attacks at least twice a month. The patients used each treatment candesartan, propranolol, or placebo for 12 weeks and also underwent four weeks before start and finish between each treatment without anything. As such each patient was tested for nearly a … Read more

Is Creative Diagnosis on the Rise in Dentistry?

A very interesting MyView column by the American Dental Association (ADA) is titled “Creative Diagnosis” by Jeffrey Camm, D.M.D. located over at http://www.ada.org/9151.aspx and published October 21, 2013. In the column the author touches on an issue he faces as a dentist where he has patients who have seen other dentists who were likely unethical in their treatment (and treating when it is not warranted) – a term he calls creative diagnosis. Of course one can ask, what is the motivation for creative diagnosis and one would answer money and staying afloat. Essentially the author describes several cases he has dealt with at his practice: A 16 year old patient who graduates from his pediatric practice and sees a new dentist who then says she has 16 cavities. The patient and her mother of course are upset and he reviews … Read more