High Tumor Necrosis Factor-Alpha Levels in People with New Daily Persitent Headache?
I have long thought that I have a lot of inflammation in my body, which is why I still have a headache, and was brought on by the sinus infection caused by removing my wisdom teeth. New research by Dr. Todd Rozen, at the Michigan Head Pain and Neurological Institute, suggests that almost all NDPH patients have an elevated level of tumor necrosis factor α (TNF α) in the cerebrospinal fluid (CSF). As about 30% of NDPH patients have their headaches start after an infection or illness, the possibility of a persistent state of systemic or central nervous system (CNS) inflammation comes into question. Tumor necrosis factor (TNF) α is a proinflammatory cytokine involved in brain immune and inflammatory activities, as well as in pain initiation. Elevation of CSF TNF α levels has been found in a select number of … Read more