MRI shows neural differences with teeth grinding and jaw pain

An interesting article titled “Neural Correlates of Tooth Clenching in Patients with Bruxism and Temporomandibular Disorder–Related Pain,” written by Theo J. M. Kluskens and et. al. appears in the Journal of Oral & Facial Pain and Headache (volume 37, Issue 2, Spring 2023, Pages 139–148). The authors sought to measure brain activity in patients with teeth grinding and jaw pain using functional magnetic resonance imaging (fMRI) to investigate whether differences when compared to those without had differennces in pain and/or neural activity. The researchers explored brain activity in 40 patients, 21 of those that bruxism and TMD pain and the remaining 19 patients were controls. The patients were asked to do a tooth-clenching task while they were having their brain scanned in a 3T MRI scanner. Patients had to mildly or strongly clench their teeth for 12 seconds and were … Read more

Tooth loss associated with brain shrinkage

An interesting article titled “Associations of Dental Health With the Progression of Hippocampal Atrophy in Community-Dwelling Individuals: The Ohasama Study,” written by Satoshi Yamaguchi and et. al. appears in Neurology, published on Juy 5, 2023. The article sought to explore associations between the number of teeth present and hippocampal atrophy older patients 55 years and older in a longitudinal study. The hippocampus is part of the brain that is important for learning and memory. With Alzheimer’s disease, atrophy of the hippocampus is a common feature but other factors, such as periodontitis (gum disease) can be seen. The researchers were under the assumption that the association between dental health and hippocampal atrophy might be due to inflammation. Gum disease is a chronic inflammatory condition, and inflammation has been shown to damage the hippocampus. The study included 172 people with an average … Read more

New Approach to help Bones Heal

An interesting article titled “Expansion of the sagittal suture induces proliferation of skeletal stem cells and sustains endogenous calvarial bone regeneration” written by Zahra A. Aldawood and et. al. appears in Proceedings of the National Academy of Sciences (vol. 120, no. 16, 2023). The article explores a new method to promote bone regeneration in mice. The researchers discuss how in newborn humans and mice and thse up to arond 2 years of age, calvarial bone defects, on the skullcap, can naturally regenerate. This abiliy to naturally heal damage to the bones that form the top of the skull, is lost in adults. The calvarial sutures are reservoirs of calvarial skeletal stem cells (cSSCs), which are cells responsible for calvarial bone regeneration. The authors believed the regenerative potential of the newborn calvaria is from the presence of a large number of cSSCs … Read more

The life events of people can be told by teeth

An interesting article titled “Parturitions, menopause and other physiological stressors are recorded in dental cementum microstructure” appears in Scientific Reports written by Paola Cerrito and et al. (vol. 10, pp. 5381, 2020). The article discusess how the life events that people have experienced can be told by their teeth. In the article the researchers conducted a study of cementum microstructure of 47 human teeth, from 15 individuals with a known life history. The teeth were processed at the Hard Tissue Research Unit of the NYU College of Dentistry. The life history events of the patiens like age, illnesses, and relocations were known and had been reported from the patients relatives. The researchers used a series of imaging techniques that illuminated cementum rings, and then linked the rings to different life stages. Doing so allowed them to reveal connections between tooth … Read more

Local Anesthesia Leads to Temporal Muscle Ossification

An interesting article titled “Traumatic myositis ossificans of the temporalmuscle after dental local anesthesia,” written by S.B. Helland and T.Ø. Pedersen appears in Clinical Case Reports (no. 11, pp. e7410, 2023). The article describes a case of a thirty year old woman who developed ossification of the temporal muscle attachment after local trauma during dental treatment which prevent her from opening her mouth. The thirty year old woman presented four months after having had a root canal treatment of a maxillary premolar tooth when local anesthesia was given near the right temporal muscle attachment. At the time she noted a sharp pain right after the injection was given. He also experienced persistent limited mouth opening after the dental treatment. Computer tomography was taken when the woman presented four months later which showed a bony growth roughly 3cm in length extending … Read more