antibiotic resistance

Platelet-rich fribin may help to carry antibiotics for oral surgery

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An interesting article titled “Can platelet-rich fbrin act as a natural carrier for antibiotics delivery? A proof-of-concept study for oral surgical procedures” written by Francesco Bennardo and et. al appears in BMC Oral Health (March 9, 2023, Vol. 23, No. 134). The article seeks to investigate the role of platelet-rich fibrin (PRF) as a carrier for antibiotics delivery for oral surgery. In the article the authors discuss how mntimicrobial resistance threatens globalhealth and that judicious prescribing of antibiotics by dental surgeons is needed to help prevent antibiotic resistance. Directly targeting tissues with local drug deliverystrategy has been shown in prior studies as a viable option to reduce unnecessaryantibiotics. In particular autologous platelet concentrates promote tissue healing by releasing autologous growth factors over time and platelet-rich fibrin (PRF) belongsto a second-generation of this type that did need manipulation after blood collection. … Read more

Antibiotic resistance: what should dentists know

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An interesting article titled “Antibiotic resistance: The silent pandemia” appears in the International Dental Journal on January 12 2023 written by Angel-Orión Salgad Peralvo and et. al. The article discusses a call to action for dentists worldwide to cut back on their antibiotic prescribing habits arguing that 66% of antiobitics prescibed is not warranted. In the article the authors mention that dentists prescribe 10% of all antibiotics in the world. However, the way they see it, antibiotics being overly prescribed can contribute to the worldwide development of antimicrobial resistance. Antibitoics are used in dentistry for preventive purposes and to avoid systemic bacteraemia in patients at risk or to prevent possible bacterial contamination during surgery. Yet the resistance problem increases medical costs and increases mortality. Therefore they feel that dentists should change the way they prescribe antiobitics as the resistance problem … Read more