bacteria

Can you fight cavities by taking a pill?

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Researches from the University of Florida have have identified a new strain of bacteria in the mouth that may keep bad bacteria in check. They believe this could lead to the development of a supplement (a probiotic) that patients could take orally to prevent cavities. While developing an effective oral probiotic will require more research, a possible candidate organism has been identified: a previously unidentified strain of Streptococcus. To maintain a healthy mouth the oral environment must have a relatively neutral pH. When the environment in the mouth becomes more acidic, dental cavities can develop. At this point bacteria on the teeth make acid and acid dissolves the teeth. Researchers were aware that bacteria were responsible for breaking down these compounds but wanted to investigate which bacteria do this best which they found to be called A12. The researchers wondered if a probiotic formulation could … Read more

Heart Infections on the Rise in Dental Patients After Antibiotic Reductions

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In March 2008, the National Institute for Health and Care Excellence issued guidelines recommending that dentists should no longer give antibiotics before invasive treatments to people who are considered at risk of developing a life threatening heart infection. The life threatening heart infection is known as infective endocarditis and 40% of all cases are caused by bacteria in the mouth. Researchers at the University of Sheffield set out to explore the impact of these guidelines. It was found that an increase in cases of infective endocarditis was observed above what was expected. In March 2013, this increase accounted for an extra 35 cases of infective endocarditis per month. The researchers found that the number of  prescribed antibiotic prophylaxis fell by 89% from 10,900 prescriptions per month, before the 2008 NICE guidelines, to 1,235 a month by March 2008. The researchers … Read more

Bacteria and Fungus Can Team Up to Cause Cavities

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An interesting article titled “Symbiotic relationship between Streptococcus mutans and Candida albicans synergizes the virulence of plaque-biofilms in vivo,” appears in the February 2014, edition of Infection and Immunity, written by Megan L. Falsetta and et al. The article describes how although Streptococcus mutans is often cited as the main bacteria in dental caries (cavities), particularly in early-childhood caries (ECCs), it may not act alone and may team up with Candida albicans. The infection with both can double the number of caries and increase their severity as it did for rats in the study. Candida albicans adheres mainly to the cheek and tongue, while Streptococcus mutans sticks to the surfaces of teeth by converting sugars to a sticky glue-like material called extracellular polysaccharide (EPS). The researchers found that the exoenzyme that S. mutans uses to react with sugar to produce EPS also … Read more

Gum Disease Bacteria may Facilitate Rheumatoid Arthritis

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As stated over on the risks of keeping wisdom teeth page, gum disease (periodontal disease) has been shown to have associations with many different systemic diseases. One such systemic disease is rheumatoid arthritis (RA). So far, any mechanism has remained elusive. In a recent study appearing in PLoS Pathogens, researchers at the University of Louisville School of Dentistry Oral Health and Systemic Diseases and other researchers from the European Union’s Gums and Joints project have uncovered how the bacteria responsible for periodontal disease known as Porphyromonas gingivalis effects rheumatoid arthritis. The researchers showed that this bacteria leads to faster progression, greater severity and earlier onset of RA and can cause bone and cartilage destruction. The researchers found the bacteria produces a unique enzyme, peptidylarginine deiminanse (PAD), which enhances collagen-induced arthritis (CIA), which is an arthritis produced in the lab designed … Read more

Removing Wisdom Teeth May Improve The Periodontal Health of Remaining Teeth

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An interesting article titled “Removal of Symptomatic Third Molars May Improve Periodontal Status of Remaining Dentition,” by Carolyn Dicus-Brookes and et al. appears in the Journal of Oral and Maxillofacial Surgery (vol. 71, pp. 1639-1646, 2013). The article seeks to explore the impact of removing wisdom teeth on the periodontal status of adjacent second molars and other teeth located in the mouth specifically for patients who have mild symptoms of pericoronitis. As discussed recently over at Upcoming Changes to JOMS and AAOMS in 2014, select articles in JOMS will have press releases written by AAOMS staff to accompany them. This is one of those articles so that feature appears to have already been rolled out. To get an idea of what the press release entails I will briefly describe it. It is very short (less than 10 sentences) and fits … Read more