Stannous Flouride Combination Can Eliminate Dental Cavities

An interesting article titled “Iron oxide nanozymes stabilize stannous fluoride for targeted biofilm killing and synergistic oral disease prevention” written by Yue Huang and et. al. appears in Nature Communications, vol. 14, No. 6087, 2023. The article discusses a potent therapeutic synergism using approved agents while providing facile stannous fluoride stabilization, to help prevent oral disease and dental caries (cavities). The authors describes a new method for using iron oxide nanozymes to stabilize stannous fluoride and improve the ability to kill biofilms. Biofilms are communities of bacteria that can form on teeth and other surfaces in the mouth. They are difficult to remove and can lead to tooth decay and other oral diseases. Stannous fluoride is an effective antimicrobial agent, but it is unstable and can be difficult to deliver to the site of infection. Ferumoxytol, an iron replacement, stabilizes stannous fluoride … Read more

Dentists Find Additional Bacteria Species Involved with Tooth Decay

An interesting article titled “Selenomonas sputigena acts as a pathobiont mediating spatial structure and biofilm virulence in early childhood caries,” written by Hunyong Cho and et. al. appears in Nature Communications (vol. 14, no. 1, 2023). The article seeks to study if other bacteria besides Streptococcus mutans are involved with tooth decay and cavities in children, also known as dental caries. Prior to the study it was believed that S. mutans and other acid-making bacteria are adequately removed by teeth-brushing and oral care, and this creates a protective biofilm, or plaque, on teeth. If the plaque is left in place for too long, bacteria consumes sugars from food and drinks and coverts them to acidsm which erode the enamel of affected teeth, in time creating cavities. The article investigated the role of Selenomonas sputigena (S. sputigena) in early cavities in children. S. … Read more

Few Children Under 1 See a Dentist

Unfortunately, new research has shown that few children under the age of 1 are seeing a dentist. This was touched on in an earlier blog post over at https://blog.teethremoval.com/will-health-care-reform-result-in-more-dental-visits/ where it was mentioned that for children between ages 1 and 4 around 60% of them have seen a medical doctor (physician) during the year, but not a dentist. The new research appears in an article titled “Factors Associated With Dental Care Utilization in Early Childhood,” by Denise Darmawikarta and et al. which was published online in Pediatrics in May 2014. The study looked at 2505 children in Toronto, Canada, who were seen for primary health care between September 2011 and January 2013. The study was past of TARGet Kids (The Applied Research Group for Kids), a collaboration between doctors and researchers from St. Michael’s Hospital and the Hospital for Sick Children in … Read more

Association Between Partially Erupted Mandibular Third Molar and Caries in Distal Second Molar

An interesting article titled “Association between the presence of a partially erupted mandibular third molar and the existence of caries in the distal of the second molars,” appears in the International Journal of Oral and Maxilofacial Surgery by S. G. M. Falci and et. al. (October 2012, pp. 1270-1274). The article mentions how previous studies have shown that caries on the mandibular second molar due to the presence of partially erupted third molars has varied between 7% and 32%. The article criticizes prior work where studies based their prevalence data on panoramic radiographs which is not as good as periapical radiographs when diagnosing caries. The authors state “The lack of sample characterization, the absence of sample calculation, the deficient or inadequate statistical analysis and the absence of a description of the eligibility criteria, discredits the scientific evidence of these previous … Read more