del-1

A recent study which appeared in Nature Immunology shows that the deterioration in gum health which occurs with increasing age is associated with a drop in the level of a chemical called Del-1. Periodontitis is a disease of the gums which causes bleeding and bone loss which can, over time, lead to loss of teeth. Periodontitis  is caused by an over-active immune response to bacteria that grow in the mouth. As people age they are more likely to suffer from inflammatory diseases, including gum disease. The new research investigated gum disease in young and old mice and found that an increase in gum disease in the older animals was accompanied by a drop in the level of Del-1. Del-1 is known to restrain the immune system by stopping white blood cells from sticking to and attacking mouth tissue. In mice that had … Read more