dentistry

Investigation Between Oral Health and Alzheimer’s Disease

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Alzheimer’s disease is a progressive neurodegenerative disorder that attacks the brain cells responsible for memory, thinking, and behavior. Over time, the symptoms worsen, leading to memory loss, confusion, difficulty with language and reasoning, and changes in personality and behavior. In the later stages, sufferers may require assistance with daily activities. The exact cause of Alzheimer’s is unknown, but it’s linked to the buildup of abnormal proteins in the brain. Maintaining good oral health is essential for a good smile, but a new report suggests it may also play a role in protecting your brain. The CareQuest Institute for Oral Health has released a study highlighting a potential connection between poor oral health and an increased risk of developing Alzheimer’s disease and related dementias (ADRD). The study was published at https://www.carequest.org/system/files/CareQuest-Institute_Poor-Oral-Health-May-Contribute-to-the-Risk-of-Dementia-Visual-Report_4.25.24.pdf The report raises several interesting points. Adults diagnosed with Alzheimer’s … Read more

Sweeten dental injections to reduce pain for kids

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A new article titled “Efficacy of administering a sugar-free flavor before dental injections on pain perception in children: A split-mouth randomized crossover clinical trial” appears in International Journal of Paediatric Dentistry written by Ola B. Al-Batayneh and et. al. (April 16, 2024). Getting a shot at the dentist can be scary for kids, but a this study suggests a simple trick might help: sugar-free flavoring. Researchers compared giving kids a sugar-free flavor before a dental injection to giving them plain water. The study included 84 children ages 4 to 9 who needed injections on both sides of their mouths. One side received injections after a sugar-free flavor was applied, and the other side received water. Image by Jenny Friedrichs from Pixabay The kids had their heart rates measured as an objective indicator of pain using a fingertip pulse oximeter. Further … Read more

Missing Teeth Could Lead to More Gray Hair

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An interesting article titled “Premature gray hair development in the interbrow region owing to the loss of maxillary first molars in young mice” written by Masae Furukawa and et. al. appears in Genes to Cells (published 20 February 2024). The article suggests that losing your teeth might also be affecting your appearance in a way you wouldn’t expect and suggests a link between missing teeth and premature graying hair in the eyebrows. Image by Pexels from Pixabay Chew on This: Less Chewing, More Gray Hair? This study, the first of its kind, investigated the connection between reduced chewing due to tooth loss and the development of gray hair. Researchers extracted upper first molars from young mice and observed them for three months alongside a control group that kept their teeth. Mice missing teeth developed gray hair between their eyebrows, while … Read more

Microscopic Robots Could Revolutionize Stopping Infections

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Its possible one day that tiny robots one day can swim through your bloodstream, delivering medication directly to infected cells or removing harmful bacteria. This is the future of medicine, and it’s being made possible by microrobotics. Microrobots are micrometer-sized robots that have the potential to revolutionize healthcare. They can be used for a variety of purposes, including: Researchers at the University of Pennsylvania propose using microrobots to deliver medication and remove biofilms more effectively. Microrobots can be powered intrinsically or extrinsically. Microrobots are still in the early stages of development, but they have the potential to transform healthcare. These microrobots may be used to target infections stuck in areas, such as between the teeth. The technology may reduce antimicrobial resistance. Image by Thor Deichmann from Pixabay Microrobots also offer a new way to collect microbial samples that could be used to diagnose other diseases. Microrobotics relies on … Read more

Brushing Regularly can Help Heart Health

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An interesting article titled “Porphyromonas gingivalis, a periodontal pathogen, impairs post-infarcted myocardium by inhibiting autophagosome–lysosome fusion” written by Yuka Shiheido-Watanabe and et. al. appears in the International Journal of Oral Science. This study investigated the molecular mechanisms underlying the adverse effects of P.g. infection on post-MI myocardial remodeling. P.g. infection impaired autophagosome–lysosome fusion, a step in the autophagy process. The study showed that the periodontal pathogen Porphyromonas gingivalis can exacerbate heart damage after a heart attack. The researchers found that the bacterium can accumulate at the site of injury and contribute to tissue damage. The mechanisms for which this occurs is stil under investigation. In an effort to understand how Porphyromonas gingivalis contributes to heart damage, the researchers developed a modified version of the bacterium that lacks a key protein called gingipain. This protein is known to protect cells from … Read more