genes

Two recent papers y researchers at the University of Pittsburgh School of Dental Medicine and their collaborators suggest that specific genetic variations may be linked to higher rates of tooth decay (cavities) and aggressive periodontitis, which is inflammation and infection of the ligaments and bones that support the teeth. Dental cavities have been found to be influenced by individual variations in a gene called beta defensin 1(DEFB1), which plays a key role in the first-line immune response against invading germs. For one of the studies, the researchers analyzed nearly 300 anonymous dental records and accompanying saliva samples from the their dental registry, assigning each case a DMFT score based on the presence of decayed teeth, missing teeth due to caries, and tooth fillings. In addition each case also received a DMFS score, based on decayed teeth, missing teeth, and filled … Read more