gum disease

Gum diease can lead to selective disarming of the immune system

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A new study has shown that bacteria responsible for many cases of periodontitis causes dysbiosis in a two prong manipulation of the immune system. The researchers say that periodontal bacterium porphyromonas gingivalis acts on two molecular pathways to block immune cells’ killing ability while preserving the cells’ ability to cause inflammation. This protects these bacteria from being removed by the immune system and leads to bone loss and inflammation which is characteristic of periodontitis. The researchers say when inflammation occurs breakdown products are produced which causes dysbiosis and creates a vicious cycle. P. gingivalis is known as a keystone pathogen. Their presence may be relatively few in the mouth but they can exert a large pull on the overall microbial ecosystem. P. gingivalis doesn’t actually cause periodontitis but is responsible for causing the process that leads to it. The researchers believe that … Read more

Oral Bacteria That Causes Periodontitis Delievers a One-Two Punch

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Oral health care workers and scientists have know for many years that bacteria cause periodontitis (gum disease); however, they were not sure exactly what bacteria was response. Recently the bacteria that causes periodontitis (gum disease) has been identified by a University of Michigan study. This bacterium is known as NI1060. It was also found that this triggers a normally protetive protein in the oral cavity called Nod1 to trigger bone destroying cells. In normal circumstances Nod1 fights harmful bacterium in the body. Hence, it was that the bacteria that causes gum disease triggers a one-two punch by also causing normally protective proteins to then destroy more bone. In normal cases No1 helps to fight infection by recruiting neutrophils which are blood cells that act as bacterial killers. Nod1 also removes harmful bacteria during infection. When periodontitis (gum disease) occurs NI1060 … Read more

Gum Disease More Common With Old Age

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A recent study which appeared in Nature Immunology shows that the deterioration in gum health which occurs with increasing age is associated with a drop in the level of a chemical called Del-1. Periodontitis is a disease of the gums which causes bleeding and bone loss which can, over time, lead to loss of teeth. Periodontitis  is caused by an over-active immune response to bacteria that grow in the mouth. As people age they are more likely to suffer from inflammatory diseases, including gum disease. The new research investigated gum disease in young and old mice and found that an increase in gum disease in the older animals was accompanied by a drop in the level of Del-1. Del-1 is known to restrain the immune system by stopping white blood cells from sticking to and attacking mouth tissue. In mice that had … Read more

Periodontal disease (gum disease) might increase the time it takes to become pregnant

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Research presented at the the European Society of Human Reproduction and Embryology earlier this year showed that periodontal disease (gum disease) might increase the length of time it takes for a woman to become pregnant. Periodontal disease has been linked to many different types of systemic disease. Periodontal disease can lead to inflammation and bleeding around the gums which can lead to spaces called periodontal pockets. The research was led by Roger Hart who is a Professor of Reproductive Medicine and is also Medical Director of Fertility Specialists of the University of Western Australia. A total of 3737 pregnant women in the study were followed and outcomes of pregnancy were looked at for 3416 of the 3737 pregnant women. It was found that women who had periodontal disease (gum disease) took around 7 months to become pregnant while those women who … Read more

How to Prevent Gum Disease and Cavities

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The following is a Guest Post by Dr. Richard Mitchell who has been a dentist for over 30 years and has experience in 6 different countries. Dr. Richard Mitchell has a website with excellent dental advice at  dental-health-advice.com It’s impossible to guarantee problem-free teeth,  but you can stack the odds in your favor by following a short routine each day! FIFTEEN MINUTES A DAY. That’s all it takes to really make a difference.  Can you find 15 minutes? Here’s a bonus. You don’t have to spend those fifteen minutes in the bathroom – with a little practice,  you can do most of the work sitting on the couch watching TV! OK,  what are the things to do? First of all,  don’t worry about the brand of toothbrush.  Like Lance Armstrong said,  “it’s not the bike”.  When we’re talking about getting … Read more