headache

New Drugs to Help Prevent Migraine in Development

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Earlier this year at the American Academy of Neurology’s 66th Annual Meeting in Philadelphia, two studies were presented which may be intriguing for those who suffer from migraine headaches. The studies explored the use of potential drugs to prevent migraine attacks from occurring. In both studies monoclonal antibodies were explored which target the calcitonin gene related peptide CGRP. Researchers have believed that CGRP is useful for migraine but drugs were never developed for it previously. One of the studies looked at 163 people who suffered from migraine between 5 and 14 days per month. These individuals received either a placebo or a IV dose of a drug ALD403. The individuals were followed for a period of 24 weeks. Those who received ALD403 had an average of 5.6 fewer migraine days per month compared to 4.6 fewer migraine days per month for … Read more

New Blood Pressure Medication for Migraines

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A new study by the Norway and the Norwegian University of Science and Technology shows that a blood pressure medication, candesartan, is as effective as propranolol which is prescribed to prevent migraine. Further, candesartan may work better for those migraine suffers who don’t find propranolol to be useful. The study by the norwegian researchers was a triple blind test which means that neither patients nor doctors nor those who analyzed the results knew whether the patients had been given the drug or a placebo. Seventy two patients took part in the study and all patients were affected by migraine attacks at least twice a month. The patients used each treatment candesartan, propranolol, or placebo for 12 weeks and also underwent four weeks before start and finish between each treatment without anything. As such each patient was tested for nearly a … Read more

Can Making Less Money Lead to Migraines?

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A study appearing by researchers in Neurology explores whether migraines limit the educational and career achievements of individuals which can lead to a lower income status. The study also explores whether problems related to low income such as stressful life events and poor access to health care increase the likelihood of developing migraines. The researchers used data from the American Migraine Prevalence and Prevention Study, a US national sample containing responses of 162,705 men and  women aged 12 and older who had some migraine symptoms able to be identified, their age, and household income. The authors defined low income as less than $22,500 per year for the household and high income as $60,000 per year or more. The researchers found the remission rate when migraines stop occurring for a time or for good was the same regardless of income. The researchers … Read more

Is Hashimoto’s Encephalopathy Related to New Daily Persistent Headache?

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An interesting article titled “New Daily Persistent Headache As A Presenting Symptom Of Hashimoto’s Encephalopathy,” is written by Daniel E. Jacome and located over at http://www.webmedcentral.com/wmcpdf/Article_WMC00960.pdf. The article discusses Hashimoto’s encephalopathy (HE) which is a rare autoimmune neurological disorder and how patients with this disorder may present with a headache characteristic of new daily persistent headache or atypical hemicranias continua. Patients of HE are said to have elevated serum titers of thyroid microsomal and antithyroglobulin antibodies. A reference is made to a past case of a woman who had such elevated antibodies and also a left sided headache and aphasia. The current article describes a case of a 50 year old man who had such elevated antibodies and also a persistent daily left sided headache with aphasia. Note that his brain MRI and MRA was normal. In the article it … Read more

Chewing Gum Linked to Headaches

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An interesting study and findings regarding a link between headaches and gum chewing has come from Tel Aviv University. The article was published in Pediatric Neurology and looked at 30 patients between 6 and 19 with chronic headache and who were big gum chewers. The patients were told to stop chewing gum. After 1 month, nineteen of the patients had their headache go away and 7 additional patients in the group had a decrease in the severity and frequency of their headaches. Twenty six of the patients were then told to go back to chewing gum like they used to and they all said their previous symptoms returned within days. The researchers speculate that temporomandibular joint (TMJ) dysfunction may be the likely trigger at bay. The researchers believe that TMJ overuse is causing the headaches. Other possibilities were suggested such as … Read more