Using Rifamycin for Reducing Complications After Wisdom Teeth Surgery

An interesting article titled “Evaluation of the efficacy of topical rifamycin application on postoperative complications after lower impacted wisdom teeth surgery” appears in the Journal of Stomatology, Oral and Maxillofacial Surgery written by Levent Cigerim and et. al. (online 11 May 2023, 101501). The article explores the efficacy of a single-dose of topical rifamycin application to reduce complications after wisdom teeth surgery. Rifamycin has been shown to be effective in the inflammatory phase of wound healing by inhibiting prostaglandins, TNF-α and IL-8. In the study the authors included 35 patients with bilaterally impacted lower wisdom teeth that were removed for orthodontic reasons. The patients were split into two groups where the extraction sockets were irrigated with 3 ml/250 mg of rifamycin or with saline. The patients had their pain intensity measured daily for 7 days using a visual analog scale. Mouth … Read more

Melatonin to Reduce Pain and Swelling Following Wisdom Teeth Removal

An interesting article titled “The Effect of Local Melatonin Application Following the Removal of an Impacted Mandibular Third Molar” appears in the Journal of Oral and Maxillofacial Surgery written by Shaimaa Mohsen Refahee and et. al. The article seeks to measure the effect of applying melatonin in the socket of an impacted lower wisdom tooth with osteogenic activity, painkilling effect, and anti-inflammatory effect. A prior article exploring the use of melatonin after wisdom teeth extraction has been discussed on this site before see Should Melatonin be Used for Wisdom Teeth Surgery?. In the current article, the authors conducted a prospective, randomized, blinded trial comprised of patients who required removal of the impacted lower wisdom tooth. Melatonin has antioxidant and anti-inflammatory properties and promotes osteoblast differentiation and bone formation, which could potentially limit problems like intrabony defects and bone loss associated … Read more

Laser therapy can reduce pain after wisdom teeth removal

An interesting article titled “Extraoral low-level laser therapy can decrease pain but not edema and trismus after surgical extraction of impacted mandibular third molars: a randomized, placebo-controlled clinical trial,” appearing in BMC Oral Health is written by Ehsan Momeni and et. al. (September 20, 2022, Vol. 22, 417). The article seeks to explore the impact of using a low-level diode laser on pain, swelling (edema), and jaw opening (trismus) following surgery to remove impacted lower wisdom teeth. This topic has been covered before on this site see for example the articles Laser Therapy to Reduce Pain and Improve Healing After Tooth Removal and Using Laser Therapy after Tooth Extraction to Improve Wound Healing. In the article the authors explore laser therapy as a possible alternative to techniques such as medication, cryotherapy, and surgical closure techniques to minizime complications, pain, and … Read more

Does Bromelain Impact Pain, Swelling, and Mouth Opening after Wisdom Teeth Surgery?

An interesting article titled “Oral Bromelain for the Control of Facial Swelling, Trismus, and Pain After Mandibular Third Molar Surgery: A Systematic Review and Meta-Analysis,” appears in the 2019 edition of the Journal of Oral and Maxillofacial Surgery written by Liu et al. The article seeks to explore if bromelain reduces pain and swelling and improves mouth opening after wisdom teeth removal. Bromelain is believed to decrease swelling by returning interstitial fluid and inflammatory component cells into the bloodstream and provide an anti-inflammatory effect by decreasing pain mediators such as prostaglandin E2 and substance P. Bromelain provides for systemic proteolytic enzyme therapy and is a mixture of proteolytic enzymes found in pineapple plants. The authors state a few articles in the past have explored using bromelain after wisdom teeth removal but with inconsistent results. For example one study showed bromelain … Read more