What is the norcebo effect and does it matter for dentistry?

An interesting article titled “What is the nocebo effect and does it apply to dentistry? A narrative review” written by T. Watanabe and et al. appears in the Journal of Oral Rehabilitation (2022). The article discusses the concept of a nocebo which is different than a placebo. A nocebo is where negative expectations lead to the effect of either clinical worsening, suboptimal treatment efficacy, or the occurrence of adverse events. A placebo on the other hand is where postive expectations leads to an effect that causes an improvement in symptoms. In the article the authors sought to explore the norcebo effect in dentistry which they say to date has been given very little attention which only a limited number of articles discussing it. The norcebo effect is real and has been demonstrated in numerous experimental and clinical settings, which hows … Read more