Pain

FDA warns about dental problems from buprenorphine

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The U.S. Food and Drug Administration (FDA) has issued a safety concern regarding the medication buprenorphine which is a medication used to treat opioid use disorder, acute pain, and chronic pain. Buprenorphine is often used to reduce opioid withdrawal symptoms and the desire to use opioids, without causing the cycle of highs and lows associated with abusing opioid. The FDA warning issued on January 12, 2022, states that dental problems have occured when patients take medicines containing buprenorphine that are dissolved in the mouth. In the warning, the FDA said that the dental problems can include those of tooth decay, cavities, loss of teeth, and oral infections, and can occur in those without prior dental issues. As a result of this warning, the risk of dental problems occuring will be added to the prescribing information and the patient Medication Guide … Read more

Does Bromelain Impact Pain, Swelling, and Mouth Opening after Wisdom Teeth Surgery?

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An interesting article titled “Oral Bromelain for the Control of Facial Swelling, Trismus, and Pain After Mandibular Third Molar Surgery: A Systematic Review and Meta-Analysis,” appears in the 2019 edition of the Journal of Oral and Maxillofacial Surgery written by Liu et al. The article seeks to explore if bromelain reduces pain and swelling and improves mouth opening after wisdom teeth removal. Bromelain is believed to decrease swelling by returning interstitial fluid and inflammatory component cells into the bloodstream and provide an anti-inflammatory effect by decreasing pain mediators such as prostaglandin E2 and substance P. Bromelain provides for systemic proteolytic enzyme therapy and is a mixture of proteolytic enzymes found in pineapple plants. The authors state a few articles in the past have explored using bromelain after wisdom teeth removal but with inconsistent results. For example one study showed bromelain … Read more

Man Ends His Own Life Dealing with Wisdom Tooth Pain

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Recently a 38 year year old man took his own life while he was waiting to have a wisdom tooth removed. This occurred in Southampton in England in April 2019. The man had been on a waiting list on the National Health Service (NHS) to have his wisdom tooth extracted. He came down with a severe toothache in January 2019 and saw a dentist. After seeing the dentist the man began to take large amounts of painkillers. His mother began to save up money so they could afford private treatment for the extraction. At the time of the death it was estimated the mother had saved about 900 British Pounds  of the 1,500 British Pounds needed for surgery. In the weeks leading up to the death the co-workers of the man said he was always asking to work overtime. After his … Read more

Common Types of Teeth Injuries and Their Solutions

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Although teeth are naturally resilient, they can face some problems like gum disease and tooth decay. These types of dental problems can badly damage your tooth. In the worst case scenario,  you may even lose them! However, there are some external dangers that can injure your teeth as well. Fortunately, there are treatments available which can help fix them and can decrease the chance of losing them. It is best to frequently visit your dentist for a regular checkup. Some of the common dental injuries are as follows: Fractured or Chipped Teeth Your tooth can be fractured easily especially during sports (when receiving an abrupt blow to the face). A report by the National Youth Safety Foundation says that if athletes don’t wear mouth guards for some sports, they have a 60 percent more chance of damaging their teeth. Moreover, … Read more

Low sensitivity to pain due to gene mutation

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A research team from UCL has identified a rare mutation that causes members of one family to have low sensitivity to pain. The researchers hope that the results could be used to identify new treatments for chronic pain. One in ten people experience moderate to severe disabling chronic pain. Understanding congenital analgesia, a rare inherited condition that reduces the capacity to feel physical pain, could lead to new pain relief therapies. Two mutations causing congenital analgesia are being explored by researchers working with pharmaceutical firms, but no breakthrough drugs have been developed. The researchers studied an Italian family, the Marsilis, which has six people with a distinctive pain response unique to them. The members of this family can burn themselves without feeling any pain. The family has normal intraepidermal nerve fibre density which means they are not missing any nerves. … Read more