Gene Therapy for Gum Disease

Scientists at the University of Michigan have shown that gene therapy can be used to successfully stop the development of periodontal disease. The U-M group is the first known to use the gene delivery approach to show potential in treating chronic conditions such as periodontal disease, said William Giannobile, professor at the U-M School of Dentistry. “Gene therapy has not been used in non-life threatening disease. (Periodontal disease) is more disabling than life threatening,” said Giannobile, who also directs the Michigan Center for Oral Health Research and has an appointment in the U-M College of Engineering. “This is so important because the next wave of improving medical therapeutics goes beyond saving life, and moves forward to improving the quality of life.” The preclinical study offers was a collaboration with the Seattle-based biotechnology company Targeted Genetics. In July, Targeted Genetics released … Read more