periodontitis

New Antibiotic Shows Promise in Fighting Gum Disease and Potentially Other Serious Illnesses

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A recent study published in the Journal of Oral Microbiology (Nik Yakar and et. al., Targeted elimination of Fusobacterium nucleatum alleviates periodontitis Volume 16, 2024 – Issue 1), suggests a potential breakthrough in the fight against periodontitis, a serious gum disease. Researchers found that a narrow-spectrum antibiotic, FP-100 (hygromycin A), effectively eliminates Fusobacterium nucleatum (F. nucleatum), a key bacterium linked to the onset and progression of periodontitis. F. nucleatum is a particularly concerning bacterium because it has been implicated in various systemic diseases beyond gum disease, including colorectal cancer and Alzheimer’s disease. How FP-100 Works: The study demonstrated that FP-100 specifically targets F. nucleatum without significantly disrupting the overall balance of the oral microbiome. This is crucial, as broad-spectrum antibiotics can often have detrimental effects on beneficial bacteria in the mouth and gut. In both in vitro and in vivo models, FP-100 effectively … Read more

Matcha from Green Tea Mouthwash Shows Promise in Fighting Gum Disease

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Gum disease, also known as periodontitis, is an infection that damages the soft tissue and bone supporting teeth. Porphyromonas gingivalis (P. gingivalis )is one of the main culprits behind gum disease. If left untreated gum diesease can lead to tooth loss. The main cause of gum disease is poor oral hygiene, which allows plaque and bacteria to build up on teeth and under the gumline. Brushing teeth twice a day, flossing daily, and visiting the dentist regularly for cleanings all help to prevent gum disease. If you’re experiencing gum inflammation or discomfort, a simple saltwater rinse can offer relief. Mixing a half-teaspoon of table salt into warm water creates a soothing solution. Swishing with this rinse can help reduce inflammation and ease any pain you might be experiencing. Smoking and excessive alcohol consumption are known culprits in worsening gum disease. … Read more

Association between brain and periodontitis

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An interesting article titled Periodontitis causally affects the brain cortical structure: A Mendelian randomization study written by Mengqiao Wang and et. al. appears in the Journal of Periodontal Research, published December 7, 2023. The authors sought out to estimate whether genetically proxied periodontitis impacts the brain cortical structure. The lines between oral and neurological health blur further, as the article reveals that gum disease isn’t just a dental concern, but can potentially impact the way our brains are wired. The researchers found a causal link between periodontitis, also known as gum disease, and changes in the structure of the brain’s cortex. This is the first study to show such a connection, and may open a new avenue for understanding neurological diseases. To uncover a potential cause-and-effect link between gum disease and brain structure, researchers employed a clever technique called “Mendelian randomization.” … Read more

Periodontitis has a relationship to atrial fibrosis in atrial fibrillation

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An interesting article titled “Relationship Between Periodontitis and Atrial Fibrosis in Atrial Fibrillation: Histological Evaluation of Left Atrial Appendages” appears in the JACC: Clinical Electrophysiology written by Shunsuke Miyauchi and et. al. (Volume 9, Issue 1, January 2023, Pages 43-53). The article seeks to explore the relationship of periodontitis with atrial fibrillation (AF) and atrial fibrosis. Periodontitis (periodontal disease) is an inflammatory disease where bacteria accumulates at the gum line. The likelyhood of periodontal disease occurring later in life in the wisdom tooth region is a reason dentists and oral surgeons give to support removing healthy wisdom teeth in the teenage and twenty years of age. Various associations to periodontitis has been showed over the years as covered before on this site see for example the posts Omega 3 Fatty Acids Inversely Proportional to Periodontitis, Blueberry extract could help treat periodontitis, Estrogen … Read more

Physical activity can help reduce gum disease

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An interesting article titled “Leisure-Time and Occupational Physical Activity Demonstrate Divergent Associations with Periodontitis: A Population-Based Study,” appears in the January 2, 2023, edition of Journal of Clinical Periodontology written by Marruganti Crystal et al. The article discusses how physical activity can help to reduce inflammation, which can potentially decrease the risk of developing periodontitis also known as gum disease. Reducing gum disease has been discussed before on this site, see for example the posts Blueberry extract could help treat periodontitis and Natural Supplements to Improve your Periodontal Health. In the article the authors examine data from the U.S. National Health and Nutrition Examination Survey (NHANES) 2009-2014 database. They retrieved data from 10,679 adults and assessed physical activity from the Global Physical Activity questionnaire which classified activity as either high or low leisure-time or occupational activity. A full-mouth periodontal examination was … Read more