Association between brain and periodontitis

An interesting article titled Periodontitis causally affects the brain cortical structure: A Mendelian randomization study written by Mengqiao Wang and et. al. appears in the Journal of Periodontal Research, published December 7, 2023. The authors sought out to estimate whether genetically proxied periodontitis impacts the brain cortical structure. The lines between oral and neurological health blur further, as the article reveals that gum disease isn’t just a dental concern, but can potentially impact the way our brains are wired. The researchers found a causal link between periodontitis, also known as gum disease, and changes in the structure of the brain’s cortex. This is the first study to show such a connection, and may open a new avenue for understanding neurological diseases. To uncover a potential cause-and-effect link between gum disease and brain structure, researchers employed a clever technique called “Mendelian randomization.” … Read more

Periodontitis has a relationship to atrial fibrosis in atrial fibrillation

An interesting article titled “Relationship Between Periodontitis and Atrial Fibrosis in Atrial Fibrillation: Histological Evaluation of Left Atrial Appendages” appears in the JACC: Clinical Electrophysiology written by Shunsuke Miyauchi and et. al. (Volume 9, Issue 1, January 2023, Pages 43-53). The article seeks to explore the relationship of periodontitis with atrial fibrillation (AF) and atrial fibrosis. Periodontitis (periodontal disease) is an inflammatory disease where bacteria accumulates at the gum line. The likelyhood of periodontal disease occurring later in life in the wisdom tooth region is a reason dentists and oral surgeons give to support removing healthy wisdom teeth in the teenage and twenty years of age. Various associations to periodontitis has been showed over the years as covered before on this site see for example the posts Omega 3 Fatty Acids Inversely Proportional to Periodontitis, Blueberry extract could help treat periodontitis, Estrogen … Read more

Physical activity can help reduce gum disease

An interesting article titled “Leisure-Time and Occupational Physical Activity Demonstrate Divergent Associations with Periodontitis: A Population-Based Study,” appears in the January 2, 2023, edition of Journal of Clinical Periodontology written by Marruganti Crystal et al. The article discusses how physical activity can help to reduce inflammation, which can potentially decrease the risk of developing periodontitis also known as gum disease. Reducing gum disease has been discussed before on this site, see for example the posts Blueberry extract could help treat periodontitis and Natural Supplements to Improve your Periodontal Health. In the article the authors examine data from the U.S. National Health and Nutrition Examination Survey (NHANES) 2009-2014 database. They retrieved data from 10,679 adults and assessed physical activity from the Global Physical Activity questionnaire which classified activity as either high or low leisure-time or occupational activity. A full-mouth periodontal examination was … Read more

Dentists Seek new Guidelines for Gum Disease

An interesting article titled “When is periodontal maintenance not enough?: The need for clinical guidance,” appears in the Journal of the American Dental Association published on January 21, 2023, written by Stephen K. Harrel and et. al. The article discusses how dentistry should seek to make new guidelines that address the management of periodontal patients who have continued inflammation. In the article discussion is made of how scaling and root planing is typically the first treatment for periodontal disease does not always eliminate inflammation. The initial treatment of periodontal disease consists of the removal of biofilm and calculus and patient education to help them continue to maintain oral hygiene in the future. The authors feel that in the case when inflammation persists, dentists should discuss to the patient advanced therapies and the risks of not undergoing these therapies while also … Read more

Does a Parasite in the Mouth Contribute to Periodontitis?

An interesting article titled “Entamoeba gingivalis Causes Oral Inflammation and Tissue Destruction,” appears in the Journal of Dental Research written by X. Bao and et al. (vol. 99, no. 5, pp. 561–567, 2020). The article seeks to explore the protozoan Entamoeba gingivalis (E. gingivalis) in inflamed periodontal pockets. In the article, the authors sought to validate the frequency of the Entamoeba gingivalis by analyzing the gums of 158 people with periodontitis and healthy controls using polymerase chain reaction and microscopy tests. A total of 107 of the people in the study were healthy controls while 51 had periodontitis. For those healthy control patients, E. gingivalis was detected in oral cavities in 15% of these patients. For those with periodontitis, E. gingivalis was detected in 77% of inflamed periodontal sites and 22% of healthy sites. The authors state “In conjunction with abundant … Read more