platelet-rich fibrin

Platelet-rich fribin may help to carry antibiotics for oral surgery

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An interesting article titled “Can platelet-rich fbrin act as a natural carrier for antibiotics delivery? A proof-of-concept study for oral surgical procedures” written by Francesco Bennardo and et. al appears in BMC Oral Health (March 9, 2023, Vol. 23, No. 134). The article seeks to investigate the role of platelet-rich fibrin (PRF) as a carrier for antibiotics delivery for oral surgery. In the article the authors discuss how mntimicrobial resistance threatens globalhealth and that judicious prescribing of antibiotics by dental surgeons is needed to help prevent antibiotic resistance. Directly targeting tissues with local drug deliverystrategy has been shown in prior studies as a viable option to reduce unnecessaryantibiotics. In particular autologous platelet concentrates promote tissue healing by releasing autologous growth factors over time and platelet-rich fibrin (PRF) belongsto a second-generation of this type that did need manipulation after blood collection. … Read more

Treating with Platelet Rich Fibrin After Wisdom Teeth Removal

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An interesting article titled “Evaluation of Treatment Outcome After Impacted Mandibular Third Molar Surgery With the Use of Autologous Platelet-Rich Fibrin: A Randomized Controlled Clinical Study,” appears in the Journal of Oral and Maxilofacial Surgery written by Nilima Kumar and et al. (vol 73, pp. 1042-1049). The article sets out to explore the effect of platelet-rich fibrin (PRF) on postoperative pain, swelling, trismus, periodontal healing near the second molar, and progress of bone regeneration in upper wisdom teeth extraction sockets. Clinicians have identified a subpopulation of patients having wisdom teeth removed that are at ‘‘high risk’’ for periodontal defects after wisdom teeth removal Las Vegas (such as greater than 26 years old, pre-existing periodontal defects [attachment level, >3 mm; probing depth, >5 mm]; and horizontal or mesioangular impaction). The authors studied a patient sample that consisted of 31 patients with … Read more