sleep deprivation

Less sleep may increase cavities risk

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An interesting article titled “Association between sleep duration and dental caries in a nationally representative U.S. population” written by Abdullah Alawady and et. al. appears in BMC Oral Health (vol. 23, Article number 497, 2023). The article seeks to establish the relationship between sleep duration and dental caries (cavities). The authors used data from the 2017-2018 U.S. National Health and Nutrition Examination Survey to explore 5,205 patients age 16 and older who completed a dental exam and sleep questionnaire. They performed regression analyses to reveal a statistically significant negative relationship between caries and sleep duration. It was found that those who have an average sleep duration of seven or more hours per night were less likely to have caries compared to people who slept less than seven hours (95% confidence interval 0.33 to 0.82; p < 0.05). Specifically 88.9% (4630/5205) of the … Read more

Sleep Deprivation and the Biological Mechanisms of Chronic Migraine Headache

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Scientists from the Missouri State University’s Center for Biomedical & Life Sciences have found new research to suggest sleep deprivation leads to changes in the levels of key proteins that facilitate events involved in the underlying pathology of migraine. “Previous clinical data support a relationship between sleep quality and migraine,” said Paul L. Dunham, Ph.D. “so we used an established model of sleep deprivation to measure levels of proteins that lower the activation threshold of peripheral and central nerves involved in pain transmission during migraine. We found that REM sleep deprivation caused increased expression of the proteins p38, PKA, and P2X3, which are known to play an important role in initiating and sustaining chronic pain.” “So little is known about the biological mechanisms that underlie how certain factors trigger a migraine attack,” said David Dodick, M.D., “This is important work … Read more