Depression Drugs (SSRIs) Linked to Dental Implant Failure

The Selective Serotonin Reuptake Inhibitors (SSRI) drugs are known to be the most widely used for depression. In a new study by the International and American Associations for Dental Research it has shown that SSRIs can reduce bone formation and lead to an increased risk of bone fracture. The study looked specifically at osseointegration implants and the risk of failures. The study was conducted on patients with dental implants from January 2007 to January 2013. A total of 916 dental implants in 490 patients were explored with 94 implants on 51 patients using SSRIs. The specific data analysis used generalized estimation equations models and Kaplain-Meier analysis. After 3 to 67 months of follow-up, 38 dental implants failed and 784 were successful in those without SSRIs and 10 dental implants failed an 84 were successful in SSRI users. When compared with … Read more