teeth

Oral Bacteria May Lead to More Heart Disease

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An interesting article titled “Associations of genetic and infectious risk factors with coronary heart disease” appears in eLife published on February 14, 2023, written by Flavia Hodel and et. al. The article discusses how common bacteria that has been linked with periodontal disease, oral cancers, and bad breath increase the chance of developing heart disease. In the past it has been discussed on this site how Brushing Teeth Twice a Day to Help Prevent Heart Disease and Bacterium goes from the mouth to the heart to cause disease. In the current article, the authors mention how cardiovascular diseases (CVDs) are the leading cause of mortality in the world and it is believed 17.9 million people die from CVD each year. The authors performed multiplex serological testing for persistent or frequently recurring infections and genome-wide analysis in a prospective population study. … Read more

Enamel Composition May Help Predict Tooth Health

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An interesting article titled “Mesoscale structural gradients in human tooth enamel” appears in the Proceedings of the National Academy of Sciences written by Robert Free and et. al. (vol. 119, no. 52, pp. e2211285119, December 19, 2022). The article explores the hierarchical architecture of human enamel which is integral to the function of human teeth. In the article, discussion is made of how tooth decay has lead to many dental visits due to cavities. There is not much known about how or why many people experience tooth enamel decay or congenital conditions. In the article, the authors used synchrotron X-ray diffraction at submicrometer resolution technology, to observe tiny differences on the order of picometers in the crystallographic parameters of enamel crystallites, which they linked to the presence of ions such as magnesium and sodium or carbonate. Features of enamel at length scales smaller … Read more

Using the sedative Remimazolam for oral surgery

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An interesting article titled “Can Remimazolam Be a New Sedative Option for Outpatients Undergoing Ambulatory Oral and Maxillofacial Surgery?” appears in the Journal of Oral and Maxillofacial Surgery written by Zijian Guo and et. al. (Available online 16 September 2022). The article discusses the sedative remimazolam and its possibility to sedate in oral surgery as effectively as midazolam. In the article the authors discuss how patients can receive dental treatment with more comfort using sedation. Midazolam is widely used in oral and maxillofacial surgery but has side effects of increased accumulation and respiratory depression. Remimazolam has similar pharmacological effects to midazolam but has rapid onset, fast metabolism, less potential adverse effects. Remimazolam has a a mean half-life of between 0.5 and two minutes and a terminal half-life in plasma of 37 to 53 minutes.  The authors conducted the first ever … Read more

World record set by nine year old’s wisdom tooth extraction

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Recently, a nine year old in Virginia has become the youngest person according to Guinness World Records to have a wisdom tooth extracted. The nine year old boy was 9 years and 327 days old when he had the wisdom tooth extracted. The boy learned that he needed the extraction when his orthondontist in Virginia noticed on a 3D x-ray that he had a wisdom tooth and a molar growing on top of each other. This was in the upper left area of his mouth. The boy said he could not feel the tooth growing but his orthodontist wanted it removed so that the molar could drop in his mouth properly. The boy was referred to an oral surgeon in Virginia. The oral surgeon confirmed wha the orthondotist had said, the wisdom tooth needed to be removed in order to … Read more

Dentists Find Additional Bacteria Species Involved with Tooth Decay

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An interesting article titled “Selenomonas sputigena acts as a pathobiont mediating spatial structure and biofilm virulence in early childhood caries,” written by Hunyong Cho and et. al. appears in Nature Communications (vol. 14, no. 1, 2023). The article seeks to study if other bacteria besides Streptococcus mutans are involved with tooth decay and cavities in children, also known as dental caries. Prior to the study it was believed that S. mutans and other acid-making bacteria are adequately removed by teeth-brushing and oral care, and this creates a protective biofilm, or plaque, on teeth. If the plaque is left in place for too long, bacteria consumes sugars from food and drinks and coverts them to acidsm which erode the enamel of affected teeth, in time creating cavities. The article investigated the role of Selenomonas sputigena (S. sputigena) in early cavities in children. S. … Read more