Long Term Consequences of Traumatic Brain Injury (TBI)
An interesting article appears in the journal PLOS ONE looking at the consequences of traumatic brain injury (TBI) using rate models. The researchers used rat models and found that overtime TBI results in progressive brain deterioration characterized by elevated inflammation and suppressed cell regeneration. Long-term neurological deficits from TBI related to inflammation may cause more severe secondary injuries and even predispose people to neurodegenerative diseases later in life. Traumatic brain injuries are important to study since troops in the U.S. military have increasingly suffered TBI from improvised explosive devices. One of the coauthors from the journal article (Dr. Paul R. Sanberg) says “Progressive injury to hippocampal, cortical and thalamic regions contributes to long-term cognitive damage post-TBI. Both military and civilian patients have shown functional and cognitive deficits resulting from TBI.” In the study researchers looked at different parts of the … Read more