Tramadol dexketoprofen combination effective for relieving wisdom teeth surgery pain

Effective pain control for wisdom teeth surgery continues to be an area of much interest. In an article titled “ANALGESIC EFFICACY OF TRAMADOL/DEXKETOPROFEN VSIBUPROFEN AFTER IMPACTED LOWER THIRD MOLAR EXTRACTION: A RANDOMIZED CONTROLLED CLINICAL TRIAL,” appearing in the Journal of Evidence Based Dental Practice written by C. Vallecillo and et al. (volume 21, issue 4, December 2021, 101618) the authors explore ibuprofen or tramadol-dexketoprofen as pain control after wisdom teeth surgery. In the article the researchers explored the effectiveness of Enanplus a capsule consisting of 75 mg tramadol hydrochloride and 25 mg dexketoprofen that is sold outside the U.S. Tramadol is an opioid class medication that inhibits the reuptake of noradrenaline and serotonin. Dexketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that has with fewer adverse effects than other more common NSAIDs. The authors conducted adouble-blind, parallel-group, randomized controlled clinical trial … Read more

Estimating Late Developing Wisdom Teeth

An interesting article titled “Late Developing Third Molars: a Concerning Predisposing Sign of Impaction?” was presented on July 22, 2021, at the virtual session of the 2021 International Association for Dental Research (IADR)/AADR/CADR General Session written by Denver Marchiori and et al. The research set to investigate more how the development of impacted wisdom teeth which are known to develop later and slower than fully erupted wisdom teeth. This study used longitudinal patient imaging data and quantitative analytical methods to investigate and determine the extent to which late-developing wisdom teeth are more predisposed to eruption and impaction. The authors retrospectively explored 324 maxillary and mandibular wisdom teeth by looking at cone-beam computed tomography scans and panoramic radiographs of 99 Western Canadians ages 6 to 24. rom this data a generalized estimating equation model was calculated to estimate wisdom tooth eruption status … Read more

Wisdom teeth could hold regenerative medicine answers

An interesting article titled “A single-cell atlas of human teeth” written by Pierfrancesco Pagella et al. appears in iScience (vol. 24, no. 102405, May 21, 2021). In the article the researchers analyzed five wisdom teeth that had been extracted to conduct a comprehensive single-cell atlas of the human tooth. The cells studied came from these five wisdom teeth and were extracted by dentists in Zurich. Isolating the cells from these wisdom teeth may have introduced variability between samples and some cells may not have survived the isolation process. Even so, the study found novel insights into how stem cells work which could help answer questions in regenerative medicine. In the study, the researchers at the University of Zurich and ETH Zurich used single-cell RNA sequencing to investigate cells present in dental pulp and the periodontium. The researchers compared patterns of … Read more

Womans toothache that led to Wisdom Teeth Removal Turns out to be Cancer

A 29 year old woman in Scotland began to experience pain in her mouth in September 2020 and also felt a pea-sized lump on her jawline. She thought the pain and problems were due to not having wisdom teeth extracted and that an infection had developed. She later had four wisdom teeth extracted Glasgow Dental Hospital in Glasgow, Scotland, and then spent 12 months on antibiotics. After the wisdom teeth were removed she continued to have a swollen gland or lymph node and she continued to feel something was not quite right. In January 2021, he went in for a biopsy and CT scan. Four days after these tests were done she was told she had a cancerous lump and was diagnosed with osteosarcoma cancer. She started chemotherpay in early March 2021. She later had to have bone reconstruction, skin grafts … Read more

Do Wisdom Teeth Surgery Informational Videos Decrease Anxiety?

An interesting article titled “Does Viewing a Third Molar Informed Consent Video Decrease Patients’ Anxiety?” appears in the Journal of Oral and Maxillofacial Surgery in 2018 written by Laskin et al. (vol. 76, pp. 2515-2517). The article discusses a study of 100 patients having impacted wisdom teeth removed and if watching a video during the informed consent process makes them more or less anxious. The authors were interested in such a study because in the past watching a video during the informed consent process of wisdom teeth removal has decreased anxiety in some cases but in other cases has increased anxiety. Further, if patients are more anxious prior to surgery they can be uncooperative which can cause the surgeon stress and lead to longer surgeries. In the study, 100 patients between 18 and 35 years of age having impacted wisdom … Read more