Tag Archives | gum disease

Oral Bacteria That Causes Periodontitis Delievers a One-Two Punch

Oral health care workers and scientists have know for many years that bacteria cause periodontitis (gum disease); however, they were not sure exactly what bacteria was response. Recently the bacteria that causes periodontitis (gum disease) has been identified by a University of Michigan study. This bacterium is known as NI1060. It was also found that this triggers a normally protetive protein in the oral cavity called Nod1 to trigger bone destroying cells. In normal circumstances Nod1 fights harmful bacterium in the body. Hence, it was that the bacteria that causes gum disease triggers a one-two punch by also causing normally protective proteins to then destroy more bone. In normal cases No1 helps to fight infection by recruiting neutrophils which are blood cells that act as bacterial killers. Nod1 also removes harmful bacteria during infection. When periodontitis (gum disease) occurs NI1060 will cause Nod1 to trigger neutrophils and also osteoclasts which are cells that destroy bone. The researchers are encouraged by the results in that they can help to better develop personalized therapy for dental patients. Periodontitis (gum disease) has been discussed on this site before numerous times. In one blog post it is discussed how Gum Disease Is More Common […]

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Gum Disease More Common With Old Age

A recent study which appeared in Nature Immunology shows that the deterioration in gum health which occurs with increasing age is associated with a drop in the level of a chemical called Del-1. Periodontitis is a disease of the gums which causes bleeding and bone loss which can, over time, lead to loss of teeth. Periodontitis  is caused by an over-active immune response to bacteria that grow in the mouth. As people age they are more likely to suffer from inflammatory diseases, including gum disease. The new research investigated gum disease in young and old mice and found that an increase in gum disease in the older animals was accompanied by a drop in the level of Del-1. Del-1 is known to restrain the immune system by stopping white blood cells from sticking to and attacking mouth tissue. In mice that had no Del-1, they developed severe gum disease and elevated bone loss. Further the researchers found unusually high levels of white blood cells in the gum tissue. When the researchers treated the gums of the mice with Del-1, the number of white blood cells dropped, and gum disease and bone loss were reduced. As indicated by the researchers, understanding the mechanism […]

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Periodontal disease (gum disease) might increase the time it takes to become pregnant

Research presented at the the European Society of Human Reproduction and Embryology earlier this year showed that periodontal disease (gum disease) might increase the length of time it takes for a woman to become pregnant. Periodontal disease has been linked to many different types of systemic disease. Periodontal disease can lead to inflammation and bleeding around the gums which can lead to spaces called periodontal pockets. The research was led by Roger Hart who is a Professor of Reproductive Medicine and is also Medical Director of Fertility Specialists of the University of Western Australia. A total of 3737 pregnant women in the study were followed and outcomes of pregnancy were looked at for 3416 of the 3737 pregnant women. It was found that women who had periodontal disease (gum disease) took around 7 months to become pregnant while those women who did not have periodontal disease took roughly 5 months to become pregnant. Professor Hart said “Our data suggest that the presence of periodontal disease is a modifiable risk factor, which can increase a woman’s time to conception, particularly for non-Caucasians. It exerts a negative influence on fertility that is of the same order of magnitude as obesity.” The reason why […]

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How to Prevent Gum Disease and Cavities

The following is a Guest Post by Dr. Richard Mitchell who has been a dentist for over 30 years and has experience in 6 different countries. Dr. Richard Mitchell has a website with excellent dental advice at  dental-health-advice.com It’s impossible to guarantee problem-free teeth,  but you can stack the odds in your favor by following a short routine each day! FIFTEEN MINUTES A DAY. That’s all it takes to really make a difference.  Can you find 15 minutes? Here’s a bonus. You don’t have to spend those fifteen minutes in the bathroom – with a little practice,  you can do most of the work sitting on the couch watching TV! OK,  what are the things to do? First of all,  don’t worry about the brand of toothbrush.  Like Lance Armstrong said,  “it’s not the bike”.  When we’re talking about getting plaque off your teeth,  I could say  “it’s not the brush”.  It’s HOW YOU USE IT.  And I can give you two tips right here; 1.  To get rid of the plaque off your teeth,  you actually have to brush the GUM EDGES.  That’s where the plaque sits.  All around the edges of the gums. 2. Most people brush their […]

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Vitamin D Can Help Prevent Gum Infections

A study appearing in the June 2011 issue of Infection and Immunity titled “Vitamin D-Mediated Induction of Innate Immunity in Gingival Epithelial Cells.” written by Laura McMahon and et al. (vol. 79, no. 6, pages 2250-2256), suggests that making sure you have enough Vitamin D can help with the immune defense in the oral cavity. The authors found that an innate immune regulator TREM-1 can be induced by treating gingival cells with vitamin D. While still much work needs to be done looking at how exactly vitamin D can fight infections there is potential for targeted therapies in the future. The authors state “As vitamin D and calcium defciences can lead to increased inflammation, it is reasonable to hypothesize that there is an association with periodontal disease….vitamin D-mediated gene regulation of the innate immune response may be associated with the initial defense against colonization by periodontal pathogens.” For now all you can do is make sure you have enough Vitamin D in your diet and consider taking a supplement. Periodontal disease is explained further on the risks of keeping wisdom teeth page. Periodontal disease has been linked to systemic diseases and is often a reason why oral surgeons recommend having […]

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