How does the U.S. Health Care System Differ From Other OECD Countries

An interesting article written by Victor R. Fuchs titled “How and Why US Health Care Differs From That in Other OECD Countries” appears in JAMA, January 2, 2013,Vol 309, No. 1, pp. 33-34.  The article attempts to discuss the difference between the U.S. Healthcare system and other countries in the  Organization for Economic Co-operation and Development (OECD). One way they differ is that the healthcare expenditures in the U.S. are twice as high. A second way they differ is that the share of expenditures funded by the U.S. government is lower. Most OECD countries have a tax-supported system healthcare system that is able to have lower administrative costs and is able to negotiate costs more aggressively with drug companies and physicians. Thirdly, there are differences in care with the U.S. being more technology intensive such as with MRIs. The author … Read more

The Immune System in Critically Ill Children with Influenza

An interesting article discussed the results of a study looking at the immune system in critically ill children. The article describes a study published in early 2013 in the January issue of Critical Care Medicine. Recent evidence indicates that the suppression of innate immune system function can occur in critically ill patients. In this study patients with innate immune suppression produced reduced amounts of tumor necrosis factor (TNF)-α  when their blood is stimulated with lipopolysaccharide (LPS). The article states “Results indicated that despite high levels of circulating pro-inflammatory cytokines, critically ill children with influenza demonstrated lower TNFα production capacity compared with healthy control subjects. Further, children who died from influenza had markedly lower TNFα production capacity compared with survivors.” Hence this study suggests that the reduction of immune function in these children who are critically ill may make them more prone … Read more

The Optional Alternative to Medical Injury Claims

Previously on this blog I have discussed some of the issues with medical malpractice in the United States and some potential alternatives. In this post Potential Alternatives to the Current Medico-Legal System in the United States I talk about some possible alternatives such as having some agreement directly with the physician and hence avoiding trial lawyers. In this provocative post How to Improve Your Chances to Win a Dental Malpractice Lawsuit I discuss the 4 elements you need to win a malpractice suit in the U.S. and a possible suggestion to help improve your chances of doing so. Last year, Kevin Pho known as “social media’s leading physician voice” discussed in a post written on July 16, 2012, titled “The New York medical malpractice crisis: Who’s to blame?,” how some financially struggling hospitals are going without medical malpractice insurance and just … Read more

Loneliness can tax the Immune System

Interesting research has been conducted by investigators from the Ohio State University. The research links loneliness to a number of dysfunctional immune responses which suggests loneliness may adversely affect overall health. The results were based on a series of studies on two different groups: 1) a healthy group of overweight middle-aged adults and 2) a group of breast cancer survivors with an average age of 51. Loneliness was measured using the UCLA Loneliness Scale. The researchers measured presence of antibodies against Epstein-Barr virus and cytomegalovirus in the breast cancer survivor group with 200 participants. Lonelier participants were found to have higher levels of antibodies against cytomegalovirus compared to less lonely participants. Further, those higher antibody levels were related to more depression, pain, and fatigue symptoms. No difference was found for Epstein-Barr virus antibody levels. Previous research has shown that stress … Read more

Gingivitis Bacteria Manipulate Your Immune System

An interesting article appears in the Journal of Leukocyte Biology discussing how the bacteria known for causing gum disease–Porphyromonas gingivalis–can manipulate the immune system to disable normal processes that would otherwise destroy it.The article talks about how this bacteria causes the anti-inflammatory molecule Interleukin-10 (IL-10) which inhibits the function of T-cells which would otherwise help to fight off the bacteria. The researchers discuss how it is important to understand how gingivitis bacteria affect the immune system since more than 50% of adults over 50 in the U.S. develop periodontal disease. The researchers used cells from mice that were exposed to Porphyromonas gingivalis and had some of them treated with an inhibiting antibody against IL-10 and the other portion of cells was not treated. The cells were then tested for interferon gamma production. The researchers found that an increase of interferon … Read more