nerve damage

Target specific brain cells to help with neuropathic pain

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Researchers from Rutgers University have explored treating chronic neuropathic pain which affects over 1 million Americans. Neuropathic pain results when nerve damage is caused due to injury, surgery or a some disease. Researchers showed that pain could be reduced in animals when microglia brain cells are targeted which are supposed to provide immunity. The researchers say that the microglia brain cells are supposed to be beneficial to the nervous system but in those with neuropathic pain these cells known as microglia have proliferated and instead become toxic. The researchers say that if they catch the injury within one to five days to inhibit microglia after nerve injury the development of chronic pain can be partially reversed. Neuropathic pain persists after the nerve has healed and is often resistant to normal pain medications. In lab mice the researchers used chemotherapy drugs to prohibit the microglia brain immune … Read more

Potential Risks of Surgery for Wisdom Teeth (Third Molars)

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M. Anthony Pogrel in his article “What Are the Risks of Operative Intervention?” in the Journal of Oral and Maxilofacial Surgery vol. 70, pp. 33-36, 2012, suppl. 1, goes into complications associated with removing impacted wisdom teeth (third molars). I have previously explored this topic in detail over at http://www.teethremoval.com/complications.html. Although I did a poor job of distinguishing actual complications from negligence. In the article, Pogrel describes how studies have indicated that around 10% (1 in 10) of people undergoing removal of third molars may suffer from a complication. However, most of these complications are mild and will completely resolve in time. Pogrel states “Complications from M3 removal can be divided into 2 groups: those that are short-lived and self limiting, including bleeding, inflammatory complications such as surgical site infection and alveolar osteitis, or “dry socket,” drug reactions, displaced crowns … Read more

Multi-Million Dollar Award In New York for Wisdom Tooth Extraction

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A 49 year old man had issues with a wisdom tooth. He went to several different times and had him attempt to remove it. He was sent home believing the extraction had been performed. However, the dentist had stopped the extraction after learning that the tooth was fused to the bone. Several hours after returning home, the man was rushed to the emergency room and was diagnosed with air emphysema and residuals roots by an oral surgeon. The oral surgeon than extracted the remaining portions of the wisdom tooth. Both the oral surgeon and dentist were found liable for the man’s injuries as neither obtained informed consent for the procedures they performed. The man has been unable to return to work as a hydro-geologist, and remains totally disabled as a result of his constant pain. He suffered extensive oral nerve … Read more

Avoiding Nerve Injuries with Lower Wisdom Teeth

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A study (in press) appears in the International Journal of Oral and Maxillofacial Surgery (2012) titled “Early extraction: a silver bullet to avoid nerve injury in lower third molar removal?” by Q. B. Zhang and Z. Q. Zhang. At the beginning of the article the authors discuss how lower third molars show the highest incidence of impaction and are responsible for pathology such as pericoronitis, periodontitis, pain, cysts, tumors, and second molar-tooth crown resorption. I have discussed the risks of keeping wisdom teeth in over here http://www.teethremoval.com/risks_of_keeping_wisdom_teeth.html The authors also discuss the complications associated with removal of third molars which I have elaborated on in great detail here http://www.teethremoval.com/complications.html. In this study two groups of patients from China were grouped: A) those less than 23 and with immature teeth, and B) those greater than 23 and with mature teeth. Group … Read more

Reconsideration of decision making for third molar extraction

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An article recently appeared in the Journal of the Korean Association of Oral and Maxillofacial Surgery titled “Reconsideration of decision making for third molar extraction, “(vol. 37, pages  343-348, 2011) by Wonse Park and et al. I am unable to read the article since it is in Korean but the abstract is in English. The introduction of the article states “Third molar extraction is one of the most common procedures in oral and maxillofacial surgery. The impacted third molar causes many pathological conditions, such as pericoronitis, caries, periodontitis, resorption of adjacent teeth, and cyst or tumors associated with impacted teeth. Extraction is often considered the treatment of choice for impacted lower third molars. On the other hand, imprudent extraction of deeply impacted third molars can cause permanent complications, such as inferior alveolar nerve damage. Therefore, guidelines for the extraction of … Read more