periodontal disease

Gingivitis Bacteria Manipulate Your Immune System

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An interesting article appears in the Journal of Leukocyte Biology discussing how the bacteria known for causing gum disease–Porphyromonas gingivalis–can manipulate the immune system to disable normal processes that would otherwise destroy it.The article talks about how this bacteria causes the anti-inflammatory molecule Interleukin-10 (IL-10) which inhibits the function of T-cells which would otherwise help to fight off the bacteria. The researchers discuss how it is important to understand how gingivitis bacteria affect the immune system since more than 50% of adults over 50 in the U.S. develop periodontal disease. The researchers used cells from mice that were exposed to Porphyromonas gingivalis and had some of them treated with an inhibiting antibody against IL-10 and the other portion of cells was not treated. The cells were then tested for interferon gamma production. The researchers found that an increase of interferon … Read more

The Body Fights Gum Disease Better When You Are Not Fat

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An interesting study was conducted by researchers at Case Western Reserve University School of Dental Medicine. The study included 31 obese people with gum disease. Half of those in the group with an average BMI of 39 had gastric bypass surgery and had had fat cells from the abdomen removed. This half did better than a control group of people with an average BMI of 35 who did not have gastric bypass surgery or had fat removed. It was stated that “All study participants underwent nonsurgical periodontal treatments of scaling/root planing and oral hygiene instructions for home care. While both groups showed improvement, the surgery group did even better on the measures for periodontal attachment, bleeding, probing depths and plaque levels.” Periodontal disease is a potential risk of keeping wisdom teeth and is discussed in more detail over at http://www.teethremoval.com/risks_of_keeping_wisdom_teeth.html. Periodontal disease has … Read more

Periodontal disease may associate with breast cancer

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An interesting study was published in Breast Cancer Res Treat (vol 127, pages 497 – 502, 2011) titled “Periodontal disease may associate with breast cancer,” by Birgitta Soder and et al. The study evaluated the association between periodontal disease and the incidence of breast cancer in a prospective study of 3273 randomly selected subjects aged 30 to 40 at baseline. The authors open by discussing how periodontal disease is characterized by chronic infection and inflammation leading to destruction of the bone surrounding the teeth. Some studies estimate that between 15 to 35% of the adult population in industrialized countries suffers from periodontal disease. Periodontal disease is initiated by a biofilm of bacteria on the teeth which triggers an immune-inflammatory response in the adjacent host tissues. Periodontal disease is of particular importance when considering whether or not to have wisdom teeth … Read more

American Dental Association Toothflix Demo Series

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Recently the American Dental Association (ADA)  has released a Patient Education DVD series called Toothflix. It contains 23 different video segments which explore different topics designed to educate patients on their oral health and prevention and treatment strategies. The complete series including all 23 segments currently is available for $699. Each segment is around 3 to 6 minutes long. It is intended to be played on a TV and DVD player in the reception or waiting area of a dental office. It could also be used in actual treatment rooms perhaps to help explain more clearly certain topics to patients. In addition another use would be for when a dentist goes out into the community to give a presentation or some other event. The ADA has 7 of the segments partially available on their website for demonstration purposes. I reviewed … Read more

Periodontal disease (gum disease) might increase the time it takes to become pregnant

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Research presented at the the European Society of Human Reproduction and Embryology earlier this year showed that periodontal disease (gum disease) might increase the length of time it takes for a woman to become pregnant. Periodontal disease has been linked to many different types of systemic disease. Periodontal disease can lead to inflammation and bleeding around the gums which can lead to spaces called periodontal pockets. The research was led by Roger Hart who is a Professor of Reproductive Medicine and is also Medical Director of Fertility Specialists of the University of Western Australia. A total of 3737 pregnant women in the study were followed and outcomes of pregnancy were looked at for 3416 of the 3737 pregnant women. It was found that women who had periodontal disease (gum disease) took around 7 months to become pregnant while those women who … Read more