Could a Medication One Day Be Given Instead of Braces to Control Tooth Movement?

Recent research from Tokyo Medical and Dental University (TMDU) showed that osteocytes have a crucial role in orthodontic tooth movement as the major source of receptor activator of nuclear factor kappa-Β ligand (RANKL) which is a protein critical to bone remodeling. It is  known that the differentiation of osteoclasts is regulated by RANKL. However, the source of RANKL in the periodontal tissue during orthodontic tooth movement was not previously identified. Now thanks to the research team it is know that osteocytes mainly express RANKL and play a key role in the remodeling of  bone surrounding teeth during orthodontic tooth movement. To explore this issue, the researchers used an orthodontic tooth movement model in which open coil springs were inserted between teeth of mice to move first molars. They then injected a neutralizing antibody against RANKL intended to reduce tooth movement. The … Read more

Using imaging to assess the impaction of lower wisdom teeth as one ages

An interesting article titled “Impaction of lower third molars and their association with age: radiological perspectives,” written by Ryalat et al. appears in BMC Oral Health in 2018 (vol. 18, no. 1, Published April 4, 2018). The article explores the impaction pattern in radiographic images of wisdom teeth. The authors were motivated by the belief that if the impaction patterns of wisdom teeth can be identified this can help guide clinical decision making regarding to extract or to retain lower impacted wisdom teeth. Specifically, for the study two individuals looked at 1,198 orthopantomographs or panoramic radiographs with 1,810 impacted lower wisdom teeth or third molars. Originally a total of 4,600 orthopantomographs were retrieved from those taken at The University of Jordan Hospital between the years 2010 and 2014, but 3,402 were excluded due to patient age being outside of the … Read more

Man in China Dies Two Weeks after Wisdom Teeth Removal

Wisdom teeth surgery can in rare cases lead to death. This has been covered before on this site in blog posts such as Wisdom Teeth Removal Death in 2016 in Florida: Settlement Reached, Four and half million settlement in wisdom teeth extraction death, Two million settlement in wisdom teeth extraction death, Recent Stories on Wisdom Teeth Removal Death, Asphyxia Due to Compression of the Trachea Leading to Death After Wisdom Tooth Extraction, 12 Million Given After Wisdom Teeth Removal Caused Death, Wisdom Teeth Removal Leaves to Death Two Days After, and Air Embolism During Wisdom Teeth Removal Causes Death. In the middle of 2020 a Chinese man died after having his wisdom teeth extracted. The 26 year old man had his wisdom tooth removed at a hospital in the Hunan Province of China on May 25, 2020. He had continuous … Read more

Should we Remove Wisdom Teeth Before Bone Disease Therapy?

An interesting article titled “Pediatric-Antiresorptive Use: Should We Intervene on Third Molars Early?” written by Michael J. Cimba and et al. appears in the Journal of Oral and Maxillofacial Surgery (vol. 79, pp. 1817−1818, 2021). The article seeks to address if oral surgeons should consider preventatively extracting wisdom teeth in children before they start bone disease therapy to prevent jawbone destruction. In the article the authors discuss how removing wisdom teeth that have not yet fully developed in children before they begin antiresorptive therapies may prevent them from developing medication-related osteonecrosis of the jaw (MRONJ). MRONJ, a progressive death of the jawbone, is a side effect of antiresorptive therapy such as bisphosphonates and denosumab, which are drugs used to treat bone (osseous) diseases and cancer-related conditions. It is well known that dental extractions like removing wisdom teeth can increase the risk … Read more

Change in Taste After Wisdom Teeth Surgery

An interesting article titled “Short-Term Evaluation of Gustatory Changes After Surgical Removal of Mandibular Third Molar—A Prospective Randomized Control Trial,” appears in the 2018 edition of the Journal of Oral and Maxillofacial Surgery (vol. 76, pp. 258-266). The article sought to explore if changes in taste occur after removing wisdom teeth. In the article the authors discuss how damage to the lingual nerve and the loss of the ability to sense taste are complications that can occur after wisdom teeth surgery. The authors devised a study using 60 patients who had impacted wisdom teeth surgically removed. They selected 15 patients in each category of mesioangular, distoangular, horizontal, and vertical impacted wisdom teeth. The patients were evaluated with regards to taste testing before surgery and again 10 days after surgery. In the study each patient was given a sweet, salty, sour, … Read more