Resolvin E1 may help treat gum disease and atherosclerosis

Researchers have shown that Resolvin E1 which is a molecule naturally produced in the body from an omega 3 fish oil, prevents and treats gum disease and decreases the likelihood for advanced arterial atherosclerotic plaques to rupture and form a thrombus or blood clot. Inflammation occurs with atherosclerosis and may play a role in the development of heart attacks and stroke. There is evidence from research groups that chronic inflammatory diseases such as diabetes, colitis, heart disease, Alzheimer’s disease, rheumatoid arthritis, kidney and pulmonary diseases, and cancer can benefit from the use of the pro-resolving lipid mediators such as resolvins and lipoxins. Researchers from Boston University and The Forsyth Institute used two groups of an experimental model that possessed highly inflamed advanced atherosclerosis. The first group was treated with a solution applied on gum tissues that contained an inflammation-lowering lipid … Read more

Chronic fatigue syndrome and Gulf War illness are distinct syndromes

Researchers at Georgetown University have found two distinct molecular signatures in the brain disorders chronic fatigue syndrome (CFS) and Gulf War Illness (GWI). In the past many doctors have told patients suffering from these syndromes that the disorders are psychological in origin so this news may come as useful to patients. The work also showed two variants of GWI. The two brain disorders share have many of the commonalities, such as fatigue, pain, exhaustion after exercise, and cognitive dysfunction. According to the National Academy of Medicine, chronic fatigue syndrome affects between 836,000 and 2.5 million Americans. The disorder was believed to be psychological in origin until a 2015 review of 9,000 articles pointed to unspecified biological causes.  Gulf War Illness has developed in more than one-fourth of the 697,000 veterans in the U.S. who were in the 1990-1991 Persian Gulf War. Gulf War … Read more

Gut Microbes can Worsen Neurodegenerative Conditions

Research has shown that microbial organisms in the gut can influence health and disease in many ways. More recent research has shown that gut microbes may cause or worsen neurodegenerative conditions such as Parkinson’s disease and Alzheimer’s disease. Now researchers at the University of Louisville and University of Michigan have proposed a new term to describe an interaction between gut microbiota and the brain. The term “mapranosis” has been coined for the process by which amyloid proteins produced by microbes (bacteria, fungi and others) alter the structure of proteins (proteopathy) and enhance inflammation in the nervous system, thereby initiating or augmenting brain disease. The researchers hope that by giving the process a name a greater sense of awareness of the process will occur and help with additional research needed for therapeutic opportunities. The researchers feel it is important to define the ways … Read more

Water Test to Detect Fluoride

Researchers at the University of Bath’s Centre for Sustainable Chemical Technologies and the Water Innovation and Research Centre (WIRC) have developed a simple color changing test to detect fluoride in drinking water. The researches believe this can help prevent bone disease and fluorosis in developing countries. This is because high levels of fluoride can weaken bones, leading to fluorosis. This disease leads to irreversible deformities of the spine and joints and particularly is harmful to children. Such a topic has been covered here before see Fluoride is often added to water in developed countries to help with keeping teeth healthy and prevent tooth decay. However, in some countries there are naturally occur elevated levels of fluoride. Levels of fluoride in drinking water are regularly monitored and controlled at treatment works in developed countries. In other areas of the world there are no piped water system … Read more

Inflammation Plays a Role in Alzheimer’s disease

Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn have shown that inflammatory mechanisms from the brain’s immune system drive the progression of Alzheimer’s disease. The research provides new insights into the pathogenetic mechanisms that may hold the potential for preventing Alzheimer’s disease before symptoms show up. Alzheimer’s disease is a neurodegenerative condition that eventually leads to dementia. The disease is associated with the aggregation of small proteins called “Amyloid-beta” (Abeta), known as “plaques,” that accumulate in the brain and are believed to harm neurons. Prior studies have shown deposits of Abeta trigger inflammatory mechanisms by the brain’s immune system. Researchers believe that deposition and spreading of Abeta likely precede any clinical symptoms by decades. Even so researchers do not fully understand the processes responsible and thus believe by doing so that effective treatments to target Alzheimer’s … Read more