stimuli

An interesting article titled “Visualization of trigeminal ganglion sensory neuronal signaling regulated by Cdk5,” written by M. Hu and et al. appears in the 2022 editon of Cell Reports (Mar 8, vol. 38, no. 10, pp. 110458). The article seeks to explore some of the mechanisms underlying facial pain and used intravital imaging to compare trigeminal neuronal activities after mechanical, thermal, and chemical stimulation. The work was carried out by researchers for the NIH’s National Institute of Dental and Craniofacial Research. Orofacial pain that occurs in the oral and facial region affects 5% to 12% of the U.S. population. This pain can affect daily activities and causes many to seek medications like opioids for releif, but opioids can be addicting. Thus researchers are interested in learning more about how facial nerves process pain signals to help lead to more efficeitn … Read more