New guidelines developed by the American Academy of Neurology confirm that the drug botulinum toxin is safe and effective for treating cervical dystonia, a condition of involuntary head tilt or neck movement, spasticity and other forms of muscle overactivity that interfere with movement in adults and children with an upper motor neuron syndrome, and excessive sweating of the armpits and hands. Botulinum toxin may also be used in hemifacial spasm, blepharospasm, some voice disorders , focal limb dystonias, essential tremor and some forms of spastic bladder disorders.
This guidelines project was chaired by David M. Simpson, MD. To develop the guidelines, the authors reviewed and analyzed systematically all available scientific studies on the topic.
Since its introduction 28 years ago, botulinum toxin has become the most effective treatment for numerous movement disorders associated with increased muscle contraction. The drug is injected into affected muscles.
A surprising finding was that botulinum toxin is probably not effective in the treatment of migraine or chronic tension-type headache. “Based on currently available data, botulinum toxin injections should not be offered to patients with episodic migraine and chronic tension-type headaches,” said pain guidelines author Markus Naumann, MD, Professor of Neurology, Head of the Department of Neurology at Augsburg Hospital in Germany, and member of the American Academy of Neurology. “It is no better than placebo injections for these types of headache.”
“We found that botulinum toxin is possibly effective in relieving low back pain and therefore may be considered as a treatment option,” said Naumann. “However, our recommendation is based on data from only one study in a small number of patients. More research is needed to define the place of botulinum toxin in treating this condition, in comparison to other treatment options.”
If you are consisdering using botulinum toxin there are reports that it can damage parts of the body far away from the injection site and can cause nerve damage. Please be careful if considering this treatment.
The guidelines appeared in the May 6, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.
Thanks for the post. People should be more aware of the adverse effect of botulinum toxin.
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